Systematic errors and base quality score recalibration. by Justin M. Zook (146772)

“…<p>(a) Observed variants in the reads can result from a variety of biological causes and sequencing errors and biases. (1) Random sequencing errors are relatively rare at any given position in the reference, and are generally reflected accurately in the reported base quality score from the instrument. (2) Biological variants that are included in the SNP database (e.g., dbSNP for humans) are excluded from the base quality score recalibration (BQSR), and therefore do not decrease the empirical quality scores. (3) RNA editing can occur at frequencies less than 50%, so it can be difficult to distinguish from SSEs. …”

Changes in collagen HP, LP cross-links, and the HP-to-LP ratio. by Daphne van Geemen (272692)

TKI increases parkin ubiquitination and interaction with Beclin-1. by Irina Lonskaya (429729)

<i>Srpr</i> is a direct target of miR-330-5p in mouse keratinocyte. by Bong-Kyu Kim (3235107)

“…<p>(A) Location of the binding site for miR-330-5p in 3’UTR of <i>Srpr</i> mRNA. …”

JHMV survival and weight loss is not altered IFN-γ null mice. by Catherine M. Kerr (21492574)

JHMV replication is unaffected by the lack of IFN-γ and is repressed by the addition of exogenous IFN-γ in bone-marrow derived macrophages. by Catherine M. Kerr (21492574)

Comparison of GATK BQSR scores for recalibration based on the genome vs. recalibration based on the spike-in standards. by Justin M. Zook (146772)

Lack of NOS2 induction in xenotransplanted mouse mammary tumors. by Karen M. Henkels (3350273)

“…<p>(<b>A-D</b>) Primary breast tumor sections were incubated with rabbit anti-NOS2 IgG antibody followed by goat anti-rabbit IgG TRITC antibody and DAPI for reference. …”

Changes in stiffness at low strains as measured with indentation tests. by Daphne van Geemen (272692)

Average relative abundance change of five most abundant families in a gut simulator treated with salicylate. by Kathleen O’Connor (3920027)

“…<p>A gut simulator seeded with a human gut microbiota was treated with salicylate each day for five days at at 0.01 mg/mL (0.01X MIC, red), 0.1 mg/mL (0.1X MIC, green) and 1 mg/mL (1X MIC, purple). …”

<i>patDp</i>/+ mice have decreased tissue 5-HT and increased tissue DA levels during postnatal development. by Kota Tamada (235174)

To be funny or not to be funny: Gender differences in student perceptions of instructor humor in college science courses - Fig 2 by Katelyn M. Cooper (5634851)

Functional TRPM7 channel is expressed in mouse cortical astrocytes. by Zhao Zeng (478844)

“…<p>A. Voltage ramp (-100 to +100 mV) was applied for 4s from a holding potential of −60 mV. …”

Data_Sheet_1_Neuronal ICAM-5 Plays a Neuroprotective Role in Progressive Neurodegeneration.PDF by Katharina Birkner (150156)

“…In humans, cerebrospinal fluid from patients suffering from progressive forms of MS shows decreased sICAM-5 levels, suggesting a lack of this endogenous protective pathway in these patient groups. …”

Evolution of valve dimensions. by Daphne van Geemen (272692)

Induction of the M2 macrophage protein Arg1 in xenotransplanted mouse mammary tumors. by Karen M. Henkels (3350273)

“…<p>(<b>A-B</b>) Mouse primary breast tumors. (<b>C-D</b>) metastatic axillary tumors. …”

The hepatic cellular environment is altered with PLD inhibitors. by Karen M. Henkels (3350273)

“…<p>Liver sections were incubated with hematoxylin and eosin (<b>A-D</b>) or antibodies specific for Arg1 (<b>E-H</b>), F4/80 (<b>J-M</b>) or LY6G (<b>N-Q</b>) for immunofluorescence microscopy. …”

Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space by Charles E. Greif (21728091)

“…The complexes demonstrated submicromolar cytotoxic activity against human breast cancer cells MDA-MB-231 or MDA-MB-468 with IC₅₀’s in the range of 0.4–5.0 μM. Complex <b>2e</b> shows high potency in vitro and decreases 3D-breast cancer mammosphere viability. …”

WT and IFN-γR^-/- have similar amounts of cytokines and frequencies of immune cells in the brain following infection. by Catherine M. Kerr (21492574)

Schematic overview of the leaflet sectioning and assignment to the different experiments. by Daphne van Geemen (272692)