Packaging of multiple cleavage enzymes that target different HBV regions enhances potency and decreases resistance. by Joshua T. Schiffer (430730)

“…<p>Simulation of HBV eradication employing gene therapy following a single dose. Each data point represents number of remaining infected cells (y-axis) after a simulation with one of 36 unique parameter sets. x-axis is functional multiplicity of infection (fMOI). …”

Pharmacologic blockade of 5LO decreases Aβ peptides levels and deposition in the 3×Tg mice via the γ-secretase pathway. by Jin Chu (358006)

Classification and regression tree: CYP3A5 phenotype discriminates between cases and tolerants (EM = normal metabolizers, IM and PM = decrease function, UM and UMH = increase function). by Luciana Kase Tanno (785410)

“…<p>Classification and regression tree: CYP3A5 phenotype discriminates between cases and tolerants (EM = normal metabolizers, IM and PM = decrease function, UM and UMH = increase function).…”

The spike-in of synthetic hsa-lest-7a-5p miRNA decreases the Ct Values of extracted small RNA samples. by Marc Van Der Hofstadt (1423027)

Heterozygous TIN2-R282H mutation decreases the frequency of telomere extension by telomerase. by Amanda K. Frank (778017)

DDX5 and DDX17 decrease viral gene expression and virion production during KSHV lytic reactivation. by Praneet Kaur Sandhu (21156149)

D-4F and L-5F decrease hepatic mRNA level of genes involved in gluconeogenesis. by Kristine C. McGrath (8269155)

SARS-CoV-2-specific CD4 and cTfh responses decrease in magnitude in late convalescence. by Sushma Boppana (7181300)

Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…To mitigate the systemic adverse effects of tofacitinib, 5-ASA–PABA–MAC and 5-ASA–PABA–diamine colon-specific delivery systems were constructed, and tofacitinib azo prodrugs <b>9</b> and <b>20a–20g</b> were synthesized accordingly. …”

LiCl administered via 0.5% LiCl food pellets for 4 wks decreases GFAP levels in <i>Gfap</i>-R236H/+ mice. by Christine M. LaPash Daniels (796881)

“…<p>(A) Survival analysis for mice treated with 0.5% LiCl in food pellets for 4 wks. 94.7% (36/38) R236H/+ mice survived LiCl treatment while 100% of mice in other groups survived. …”

Primary small molecule screen to identify attenuators of CSE-induced decrease in size and increase in MUC5AC. by Pranjali Beri (14945400)

“…Hit compounds at 1 and 10μM concentrations that <b>B)</b> increased spheroid size (swell) or <b>C)</b> decreased MUC5AC staining in the lumen relative to DMSO and CSE 3%-treated bronchospheres. …”

BMP type I receptor antagonists decrease Smad 1/5/8 activity in H1299 cells. by Elaine Langenfeld (402034)

D-4F and L-5F decrease hepatic mRNA levels of genes involved in lipogenesis. by Kristine C. McGrath (8269155)

HLA-C expression levels increase and exon 1 skipping decreases as NK cells mature. by Hongchuan Li (375905)

Schematic diagram of the track and latch comparator (a) conventional track and latch comparator (b) small signal model of the comparator. by Labonnah Farzana Rahman (641767)

Decreased bleomycin-induced apoptosis in hTERT transfected MLE cells. by Nissim Arish (736264)

“…(B) Flow cytometry analysis demonstrating decreased Annexin V staining in bleomycin-treated hTERT⁺ compared to hTERT^ctrl cells. …”

miR-200b reverses EMT and decreases invasion and metastasis by PC3 cells. by LaTanya V. Williams (504683)

Pharmacokinetic analysis of LY5 in mice and normal dogs. by Peter Y. Yu (4281448)

The T37A substitution increases both H5N6 M1 protein stability and H5N6 viral replication in mammals. by Chenxi Wang (284364)

Subjects:

TreeView Images of Examples of Great Ape and HLS Gene Copy Number Increases and Decreases by Andrew Fortna (4005)

“…Specific test DNAs were, left to right, human (H) (<i>n</i> = 5), bonobo (B) (<i>n</i> = 3), chimpanzee (C) (<i>n</i> = 4), gorilla (G) (<i>n</i> = 3), and orangutan (O) (<i>n</i> = 3). …”