<i>S</i>. Typhimurium coordinates protein synthesis with protein folding capacity. by Carissa Chan (18310140)

Chemical inhibition of formins decreases actin pedestal assembly by EPEC, but not by KC12+EspF_U. by Katrina B. Velle (4330957)

Microgel assembly / dispersion are temperature dependent. by Chi-Shuo Chen (234719)

Subjects:

Mucosal vaccination with M2e5x VLP decreases innate immune cell recruitments after influenza virus infection. by Young-Tae Lee (467116)

F1 pre-dissolution, pH 6, pH 5, and pH 4 thin sections of cortical and trabecular bone. by Colleen A. Sullivan (13955253)

Lack of p23 results in decreased epidermal thickness, delayed differentiation and increased rates of proliferation and apoptosis in E18.5 skin. by Marta Madon-Simon (527400)

“…(<b>d</b>) Immunohistochemical staining for the differentiation markers loricrin, filaggrin and involucrin shows decrease in staining intensity in <i>p23</i>^<i>-/-</i> E18.5 skin sections. …”

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-6 by Mrigank Srivastava (94935)

“…Data represent at least 3–5 independent experiments. (F-I), immunohistochemistry of cath K protein in lung tissue of wild-type mice (F, H) or cath K tg mice (G, I). …”

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-0 by Mrigank Srivastava (94935)

“…Data represent at least 3–5 independent experiments. (F-I), immunohistochemistry of cath K protein in lung tissue of wild-type mice (F, H) or cath K tg mice (G, I). …”

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

nsP4-C483Y or Q192L mutations decrease sensitivity to 4′-FlU. by Peiqi Yin (6533747)

Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis by Romy M. W. Kremers (819412)

5-fold cross-validation comparison results. by Chunming Wen (17616274)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

Accumulated immature APP in response to IDN5706 is degraded by Atg5-dependent autophagy. by Viviana A. Cavieres (500139)

Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis. by Hiroyuki Mori (512656)

“…<i>n =</i> 5, data are mean ± SD. *<i>p</i> < 0.05. Uncropped western blots are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s016" target="_blank">S1 Raw Images</a>, and numerical data for all graphs are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s014" target="_blank">S6 Data</a>. …”

Inhibition of GLS1 decreases the proportion of CCR6 and CXCR3 expressing CD4⁺ T cells. by Zeynep Sener (3146064)

“…BPTES and 968 significantly decrease the proportion of CCR6 expressing cells under normoxia both at day 3 and 5, whereas 968 but not BPTES decrease the proportion of CCR6 expressing cells under hypoxia both at day 3 and 5. …”

Depletion of Atg5 inhibits IDN5706-induced autophagy, but not EDEM1 degradation. by Viviana A. Cavieres (500139)

5-HT inhibits <i>P</i>. <i>berghei</i> infection in mosquitoes. by Li Gao (131516)

“…(G) Schematic overview of AMTP and 5-HT supplementation in mosquitoes. (H) Fold change of 5-HT in mosquitoes treated with (AMTP, <i>n</i> = 6) and without (Ctrl, <i>n</i> = 6) 100 μM AMTP for 4 days (prior to blood feeding) analyzed by ELISA. …”