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461
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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462
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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463
Electrocatalytic arsenite oxidation in bicarbonate solutions combined with CO2 reduction to formate
Published 2020“…Sunlight-driven water-energy nexus technologies are receiving increasing attention. This study presents a hybrid electrochemical system that catalyzes the oxidation of As(III) to As(V) with a nanoparticulate TiO2 electrocatalyst (Ti/Ir1-xTaxOy/TiO2; denoted as an n-TEC) while simultaneously converting CO2 to formate on a Bi electrode in aqueous bicarbonate solutions at circum-neutral pH. …”
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464
Integrated planning of spare parts and service engineers with partial backlogging
Published 2017“…In a numerical study, we show that for problems with more than five types of spare parts it is preferable to use approximate evaluations as they become significantly faster than exact evaluation. …”
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465
Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes
Published 2021“…In contrast, expected changes in atmospheric N deposition will decrease the mid-term mass loss of high-quality litter by 1.4-2.2% and that of low-quality litter by 0.9-1.5% in the temperate biome. …”
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466
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467
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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468
Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter...
Published 2022“…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…”
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469
INVESTIGATION OF SPATIOTEMPORAL VARIABILITY AND CONTAMINATION OF PLASTIC MARINE DEBRIS IN QATAR’S COASTAL WATERS
Published 2015“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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470
Effect of graphene loading on thermomechanical properties of poly(vinyl alcohol)/starch blend
Published 2015“…Mechanical properties results showed that the optimum loading of graphene was 0.5 wt % in the blend. XRD studies indicated uniform dispersion of graphene in PVA/starch matrix upto 0.5 wt % loadings and further increase caused agglomeration. …”
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471
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
Published 2017“…Study quality was assessed using a National Institutes of Health assessment tool. …”
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472
Effect of gamma irradiation on the microstructure and morphology of polyethylene oxide and polyvinyl alcohol blends
Published 2010“…Thin films of a blend of 90, 75, 50 (wt/wt%) percentage of polyethylene oxide and polyvinyl alcohol were synthesized and irradiated with 5, 25, 50, 100 and 200 kGy. …”
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473
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475
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476
Experimental Investigation of Foam drilling fluid using Visualization Technique
Published 2021“…The experiments were conducted in a 6.16 m long horizontal pipe with 2.5 in. inner diameter and 4.5 in. outer diameter and annular diameter ratio of 1.8. …”
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477
The influence of aeration scheme and aeration rate on the permeate flux for wastewater treatment using membrane bioreactors: Experimental and artificial neural network modeling
Published 2021“…Furthermore, a continuous and pulsed aeration scheme (5 min on and 5 min off) was tested. …”
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478
Empower Generations: Longitudinal Study for National Capacities in Life Sciences and Healthcare
Published 2021“…However, the association between a history of EG training and the university’s GPA is significant, with a p < 0.001, OR 5.016 (2.954–8.518). …”
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479
Low electro-synthesis potentials improve permselectivity of polymerized natural phenols in biosensor applications
Published 2017“…The natural phenol-coated electrodes were stable and responsive throughout 14 days. A biosensor prototype based on acetylcholine esterase and choline oxidase was electro-coated with poly-magnolol in order to evaluate the interference-rejecting properties of the electrosynthesized film in an amperometric biosensor; a moderate decrease in ascorbic acid rejection was observed during in vitro calibration of biosensors.…”
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480
Functionalization of silica-coated magnetic nanoparticles as powerful demulsifier to recover oil from oil-in-water emulsion
Published 2021“…The %Soil slightly decreased to ∼92% with an alkaline pH or when the thickness of the silica layer increased to ≥10 nm. …”
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