Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

24 h exposure to 5 by Kelly M. Kennedy (180156)

“…Viable MCF7 cells show significant decreases with 5 mM CHC (A, #p≤0.004 compared to control (no CHC, no lactate + glucose), ‡‡p < 0.01 compared to 40 mM lactate-treated MCF7 cells, *p = 0.003 compared to all no CHC and low CHC groups). …”

Association of TILs in primary TNBC with 16 “good outcome” (no relapse within 5 years) versus 15 “poor outcome” (relapsed within 5 years; 2 patients did not have primary specimen).... by Ting-Fang He (5210948)

Overview of the PEX5 immunofluorescence staining. by Claudia Colasante (101665)

The decrease of ULK1 expression by miR-17-5p from BCG infection. by Xiangguo Duan (423329)

TG mice hearts show decreased ISO response. by Mayilvahanan Shanmugam (691549)

H₂O₂ decreased PC12 cells viability. by Guohua Ji (436621)

“…<p>MTT assay showed that 12.5∼25 µM H₂O₂ treatment had no obvious effect, while 50 µM, 100 µM, and 200 µM H₂O₂ treatment resulted in cell viability decrease by 7%, 15% and 16%, respectively. …”

Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric <i>in silico</i> ROCOCO trial by Daniëlle B. P. Eekers (5560430)

Estimation the degree of essentialized human qualities (average of the five qualities) for each of the 16 individual robots, presented as a function of the degree of human resembla... by Tatjana A. Nazir (12262825)

The field sensitivity of a pyramidal cell decreases in a high-conductance state. by Florian Aspart (3366014)

Primary samples from patients with AML: patient characteristics. by Anna Kalota (7415)

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Activation of apoptotic pathway in AML cells by Eltrombopag. by Anna Kalota (7415)

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Eltrombopag completely inhibits S-phase DNA replication as measures by BrdU/7AAD staining in AML cells lines. by Anna Kalota (7415)

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Modification of intracellular ROS level abrogates eltrombopag’s effect on AML cells. by Anna Kalota (7415)

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MOLM14 cells incubated with Eltrombopag for 6 hours show higher expression of stress response genes. by Anna Kalota (7415)

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Tacrolimus decreased SFRP2 induced nuclear NFATc3 in 2H11 endothelial cells. by Sharareh Siamakpour-Reihani (218652)

Correlation between eltrombopag’s cytotoxic effect and ROS level at various drug doses and serum concentrations. by Anna Kalota (7415)

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NSUN2-mediated m⁵C in HBV RNA contributes to HBV RNA stability. by Jiangpeng Feng (9287738)

Loss of Pcgf5 results in reduction in global H2AK119 levels. by Sha Si (2635147)

“…<p>(A) H2AK119ub1 levels in LK cells. LK cells from BM of WT and <i>Pcgf5</i>^<i>Δ/Δ</i> mice were analyzed by Western blotting using anti-H2AK119ub1 and anti-H3K27me3 antibodies at 1-month post deletion of <i>Pcgf5</i>. …”

Decrease of NF-κB activity in tumor tissue of CCR5^−/− mice. by Ju Kyoung Song (324058)

“…<p><b>A</b>, The DNA binding activity of NF-κB was determined in the nuclear extracts of the CCR5^−/− mice and CCR5^+/+ mice tumor tissues by EMSA described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033747#s4" target="_blank">material and methods</a>. …”