Lipotoxicity reduces DDX58/Rig-1 expression and activity leading to impaired autophagy and cell death by Karla K. Frietze (10770427)

“…Here we show for the first time that DDX58 protein is significantly reduced in nonalcoholic steatohepatitis (NASH) mouse model, an aggressive form of NAFLD characterized by inflammation and fibrosis of the liver. In addition to decreased expression of DDX58, we found that DDX58 activity can be attenuated by treatments with palmitic acid (PA), a saturated fatty acid. …”

Inhibition of Glioblastoma Growth by the Thiadiazolidinone Compound TDZD-8 by Diana Aguilar-Morante (237970)

“…</p> <h3>Methodology/Principal Findings</h3><p>Our data show that TDZD-8 decreased proliferation and induced apoptosis of GL261 glioblastoma cells <em>in vitro</em>, delayed tumor growth <em>in vivo</em>, and augmented animal survival. …”

Functional Implications of Novel Human Acid Sphingomyelinase Splice Variants by Cosima Rhein (168205)

“…<div><h3>Background</h3><p>Acid sphingomyelinase (ASM) hydrolyses sphingomyelin and generates the lipid messenger ceramide, which mediates a variety of stress-related cellular processes. …”

Results of MRE measurements and histological cell counts in the substantia nigra. by Elisabeth G. Hain (542261)

“…<p>MPTP induced a significant reduction in MRE elasticity (a) and viscosity (b) in the substantia nigra (mean±SEM, n(-3,3,6,10,14,18dpi) = 5). …”

Supplemental Figure S6 by David Kaczka (20728550)

“…<p dir="ltr">Transverse and sagittal sections of the lung parenchyma for a representative pig after injury showing regional expansion when airway pressure was decreased from 30 to 25 cm H2O after lung injury. …”

ApHTT in presynaptic sensory neurons is required for the initiation of LTF. by Yun-Beom Choi (602935)

“…Injection of ApHTT anti-sense oligonucleotides into the presynaptic sensory neuron lead to a decrease in ApHTT mRNA level. Confocal projection images are shown. …”

PSM cells spreading on FN-RGE matrices. by Amparo Girós (212803)

“…The scale bars represent 15 <i>µ</i>m in (A–F), 5 <i>µ</i>m (G, H) and 50 <i>µ</i>m in (I–L).…”

Initial development of Combretum leprosum Mart. seedlings irrigated with saline water of different cationic natures by Caio César Pereira Leal (6299573)

“…The experiment was carried out between the months of August and September, in a greenhouse, and the substrate used was the commercial coconut fiber wetted with aqueous solutions of sodium chloride (NaCl), calcium chloride (CaCl2) and potassium chloride (KCl) with the electrical conductivities of 0.0, 1.5, 2.5, 3.5, 4.5, 5.5 and 6.5 dS m-1. …”

Identification of the DEAD-box RNA helicase Rm62 as an interaction partner of SU(VAR)3-9. by Joern Boeke (218735)

“…Lane 1: purified recombinant GST-Rm62. Lane 2: 5 µl of a nuclear extract (NE) from <i>Drosophila</i> embryos (0–12 h a.e.l.). …”

Data_Sheet_1_Assessment of Water Quality Along the Southeast Coast of India During COVID-19 Lockdown.docx by K. Vijay Prakash (10589021)

“…A significant reduction in PM2.5 concentration (45.63%) was observed in the Ennore-Manali Industrial region.…”

Thresholding clusters by number of annotations improves precision at the expense of recall, while thresholding by fraction of unique workers who contribute multiple times to the cl... by Jenny M. Vo-Phamhi (11250803)

“…<p><b>(A)</b> Thresholding clusters by the number of annotations in the cluster improved precision by 17% while decreasing recall by 10% on average in an experiment with images of mean SNR = 5, 10, and 15 and average NND = ~ 11, 15, and 19. …”

Genotype and Mn exposure influence on <i>smf</i> gene expression. by Catherine Au (242983)

“…<i>smf-1</i> and <i>smf-3</i> mRNA levels display similar variations, increasing at low Mn exposure (0.1 mM) and decreasing upon high Mn concentrations (10 mM and 100 mM) in WT, <i>smf-1</i> and <i>smf-3</i> mutants (A, C, black, blue, orange). …”

Systemic Inhibition of NF-κB Activation Protects from Silicosis by Michelangelo Di Giuseppe (263795)

“…<div><h3>Background</h3><p>Silicosis is a complex lung disease for which no successful treatment is available and therefore lung transplantation is a potential alternative. …”

Course of blood and cerebral extracellular glucose during insulin infusion by Florian Schlenk (46916)

northern mid- to high-latitudes grassland biomass data for meta-analysis by Yifan Song (22570626)

Mid-point for open-ended income category and the effect of equivalence scales on the income-health relationship by Roger Keller Celeste (6186155)

Image1.PDF by Jing Hou (18672)

“…In the present study, G. fascicularis was subjected to heat stress at 32.0 ± 0.5°C in the lab, we found that the density of symbiotic zooxanthellae decreased significantly; meanwhile apparent bleaching and tissue lysing were observed at 10 h and 18 h after heat stress. …”

Table1.XLSX by Jing Hou (18672)

“…In the present study, G. fascicularis was subjected to heat stress at 32.0 ± 0.5°C in the lab, we found that the density of symbiotic zooxanthellae decreased significantly; meanwhile apparent bleaching and tissue lysing were observed at 10 h and 18 h after heat stress. …”

Table3.XLSX by Jing Hou (18672)

“…In the present study, G. fascicularis was subjected to heat stress at 32.0 ± 0.5°C in the lab, we found that the density of symbiotic zooxanthellae decreased significantly; meanwhile apparent bleaching and tissue lysing were observed at 10 h and 18 h after heat stress. …”

Table4.XLSX by Jing Hou (18672)

“…In the present study, G. fascicularis was subjected to heat stress at 32.0 ± 0.5°C in the lab, we found that the density of symbiotic zooxanthellae decreased significantly; meanwhile apparent bleaching and tissue lysing were observed at 10 h and 18 h after heat stress. …”