Downregulation of DOM decreases the abundance of PER and TIM. حسب Zhenxing Liu (399809)

"…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …"

Inducing proteotoxic stress in 5-HT neurons does not recapitulate a <i>Minute</i> phenotype. حسب Lisa Patricia Deliu (13570709)

IFNγ enhances the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> uptake by the human U-87 MG astroglioma cells. حسب Glaucia Vilar-Pereira (686134)

Fx treatment abrogates the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> infection of human U-87 MG astroglioma cells. حسب Glaucia Vilar-Pereira (686134)

Fx controls the TNF-enhanced Ser/5-HT-promoted <i>Trypanosoma cruzi</i> uptake by U-87 MG cells and neuromediators availability. حسب Glaucia Vilar-Pereira (686134)

Crosslinking decreases the alignment of fibers associated with individual cells migrating out of spheroids. حسب Michael Pamonag (12295175)

Tax expression is associated with decreased cellular motility. حسب Saumya Ramanayake (7879091)

Passive transfer of humanized anti-NS1 mAb 33D2 into DENV-inoculated mice decreases viral titer and NS1 level in mouse sera. حسب Sen-Mao Tien (12481273)

The influence of 5-HT on MSQ43 cells. حسب Li Gao (131516)

Additional Analysis of visually induced calcium transients in Fig 5. حسب Maureen M. Sampson (9322886)

"…(<b>A</b>) The change in the secondary response (the magnitude of the calcium decrease following the initial peak). (<b>B</b>) Change in the exponential time constant k (units 1/sec) relative to epoch 1 (defined by ΔF/F(t) = c<i>e</i>^kt) for the time between 10% and 90% of the post-stimulus peak-to-peak difference in ΔF/F. …"

HC11 cells increase Pthlh gene expression and activity via cAMP with increases in intracellular 5HT. حسب Celeste M. Sheftel (9557588)

"…<p><b>A-C.</b> 5HTP significantly increases intracellular 5HT at 12- and 72 hours post treatment compared to baseline and at 12 hours compared to lactogenic control <b>(B).…"

Antagonist dosage and occupancy for each 5-HT receptor subtype. حسب Yukiko Hori (299784)

الموضوعات:

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis حسب Jihyeon Yoon (8705706)

"…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …"

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis حسب Jihyeon Yoon (8705706)

"…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …"

Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV حسب Henryk Majczyński (830716)

"…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT₂ (Cyproheptadine; Cypr), 5-HT_2A neutral antagonist (Volinanserin; Volin), 5-HT_2C neutral antagonist (SB 242084), and 5-HT_2B/2C inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …"

Additional Analysis of visually induced calcium transients in Fig 6. حسب Maureen M. Sampson (9322886)

"…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …"

Serotonin modulates L2 neuron visually induced calcium transient kinetics. حسب Maureen M. Sampson (9322886)

"…Comparisons are two-way repeated measures ANOVA with the bracket in 5C’ indicating a significant effect of genotype (p≤0.05*).…"

Design, Synthesis, and Biological Evaluation of New Peripheral 5HT_2A Antagonists for Nonalcoholic Fatty Liver Disease حسب Minhee Kim (1592440)

"…Recent findings suggest that peripheral serotonin (5-hydroxytryptamine, 5HT) regulates energy homeostasis, including hepatic lipid metabolism. …"

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor حسب Anat Levit Kaplan (12126567)

"…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor حسب Anat Levit Kaplan (12126567)

"…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"