يعرض 121 - 140 نتائج من 65,293 نتيجة بحث عن '(( 5 ht decrease ) OR ((( 5 w decrease ) OR ( 5 ((a decrease) OR (mean decrease)) ))))', وقت الاستعلام: 1.14s تنقيح النتائج
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    Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor حسب Anat Levit Kaplan (12126567)

    منشور في 2022
    "…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"
  4. 124

    Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor حسب Anat Levit Kaplan (12126567)

    منشور في 2022
    "…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"
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    Mean decrease accuracy plots and variable importance plots for the random forest classification process of clusters 1 and 2 in study regions North and South (<i>F</i>. <i>hepatica<... حسب Andreas W. Oehm (12015558)

    منشور في 2022
    "…<p>A: study region North. B: study region South. The mean decrease accuracy plot expresses how much accuracy the model loses by excluding each variable. …"
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    RhoA gene expression and activity are impacted with increased intracellular 5HT. حسب Celeste M. Sheftel (9557588)

    منشور في 2020
    "…<p><b>A.</b><i>RhoA</i> mRNA expression is significantly upregulated with FLX and 5HTP compared to controls and is significantly decreased in FLX + MDC. …"
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