Showing 61 - 80 results of 18,502 for search '(( 5 ht decrease ) OR ((( 50 ((ms decrease) OR (a decrease)) ) OR ( 10 ng decrease ))))', query time: 0.58s Refine Results
  1. 61

    Synthesis and Biological Evaluation of Peripheral 5HT<sub>2B</sub> Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

    Published 2025
    “…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT<sub>2B</sub>) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”
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    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
  11. 71

    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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    Data-Driven Tool for Cross-Run Ion Selection and Peak-Picking in Quantitative Proteomics with Data-Independent Acquisition LC–MS/MS by Binjun Yan (17310633)

    Published 2023
    “…Proteomics provides molecular bases of biology and disease, and liquid chromatography–tandem mass spectrometry (LC–MS/MS) is a platform widely used for bottom-up proteomics. …”
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