Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”

Effect of 5-HTR blockade on reaction time in the work/delay task. by Yukiko Hori (299784)

Subjects:

Effect of 5-HTR blockade on error pattern in the reward-size task. by Yukiko Hori (299784)

Subjects:

Effect of 5-HTR blockade on error pattern in the work/delay task. by Yukiko Hori (299784)

Subjects:

Effect of 5-HTR blockade on reaction time in the reward-size task. by Yukiko Hori (299784)

Subjects:

Effect of 5-HTR blockade on reaction time in the work/delay task. by Yukiko Hori (299784)

Subjects:

Affinity analysis results (with a confidence level above 50%). by Marta R. Jabłońska (8491404)

No discernible effect of high-dose 5-HT_2AR blockade on error rates in the reward-size task. by Yukiko Hori (299784)

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Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Inhibiting translation in 5-HT neurons does not recapitulate a <i>Minute</i> phenotype. by Lisa Patricia Deliu (13570709)

Data-Driven Tool for Cross-Run Ion Selection and Peak-Picking in Quantitative Proteomics with Data-Independent Acquisition LC–MS/MS by Binjun Yan (17310633)

“…Proteomics provides molecular bases of biology and disease, and liquid chromatography–tandem mass spectrometry (LC–MS/MS) is a platform widely used for bottom-up proteomics. …”

Effects of FCCP and verapamil on MMP of T47D and HT29 cancer cells. by Jin Won Park (2901029)

Cell viability of U-87 MG cell cultures treated with Ser/5-HT or fluoxetine. by Glaucia Vilar-Pereira (686134)

Effect of 5-HTR blockade on the relationship between error rate and reaction time in the reward-size task. by Yukiko Hori (299784)

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Expression of ApoB-50 decreased lipid accumulation and inhibited HCV production. by Bei Wang (116772)

MRI imaging and analysis, revealing decreased volume and thickness of placentas exposed to intrauterine inflammation. by Solange N. Eloundou (6551627)

Anaesthesia decreases stimulus-specific suppression on probe-responses only after communication context. by Luciana López-Jury (8601540)

Overexpression of mC4 decreased membrane capacitance without altering overall excitability. by Ashley L. Comer (8299128)