Design, Synthesis, and Biological Evaluation of New Peripheral 5HT_2A Antagonists for Nonalcoholic Fatty Liver Disease by Minhee Kim (1592440)

“…Recent findings suggest that peripheral serotonin (5-hydroxytryptamine, 5HT) regulates energy homeostasis, including hepatic lipid metabolism. …”

Repetitive stress induces a decrease in sound-evoked activity. by Ghattas Bisharat (20706928)

“…<p>(a) Left: noise-evoked activity rates at different noise intensities for chronically tracked PPys cells in baseline and repeated stress conditions (<i>N</i> = 5 mice, <i>n</i> = 285 neurons, mean ± SE). Activity rates decreased during repeated stress compared to baseline (2-way ANOVA, condition F = 185.6, <i>p</i> = 4.8 × 10⁻⁴², condition: intensity interaction F = 10.37, <i>p</i> = 9.3 × 10⁻²¹, nested ANOVA (mouse nested within session), condition F = 174, <i>p</i> = 1.5 × 10⁻³⁹, condition: intensity interaction F = 12.7, <i>p</i> = 2 × 10⁻²⁶, post hoc for each level baseline versus repetitive stress <i>p</i> < 0.01 for all levels above 50 dB, all Bonferroni corrected). …”

Comparison of the ISIs that caused 0%, 50% and 100% decreases in response magnitudes (AI spikes, AI fEPSP and MGBv spikes) to succeeding tone. by Colin Xiong (9182695)

Percentage of violacein production in <i>Chromobacterium violaceum</i> by the most active synthesized 1,2,3,5-tetrazine derivatives (4a, 4b and 4c). by Jean Paul Dzoyem (6424445)

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Bach1 decreases Smad3 protein. by Katsushi Suzuki (9225735)

Data-Driven Tool for Cross-Run Ion Selection and Peak-Picking in Quantitative Proteomics with Data-Independent Acquisition LC–MS/MS by Binjun Yan (17310633)

“…In the benchmark datasets, for analytes with large content variation among samples, CRISP-DIA generally resulted in 20 to 50% relative decrease in error rates compared to other DIA tools, at both the peptide precursor level and the protein level. …”

Diallyl Trisulfide, an Active Substance from Garlic, Inhibits Female Oviposition by Decreasing the Expression of the <i>OCT</i> Gene, which is Highly Expressed in the Spermathecal... by Wen-Han Yan (20539256)

“…Conversely, triacylglycerol (TG) decreased significantly. The expression of the 5<i>-HT</i> 2<i>A</i> receptor gene, which is highly expressed in the abdomen, was significantly decreased. …”

Diallyl Trisulfide, an Active Substance from Garlic, Inhibits Female Oviposition by Decreasing the Expression of the <i>OCT</i> Gene, which is Highly Expressed in the Spermathecal... by Wen-Han Yan (20539256)

“…Conversely, triacylglycerol (TG) decreased significantly. The expression of the 5<i>-HT</i> 2<i>A</i> receptor gene, which is highly expressed in the abdomen, was significantly decreased. …”

Effects of 5-HTR blockade on incentive. by Yukiko Hori (299784)

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Parameter estimation of the data for 5-HT_1AR blockade and control in monkey KN. by Yukiko Hori (299784)

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Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…In contrast, reversing managed to natural ecosystems significantly increased NNM by 20% (9.7, 25.4%) and decreased NN by 89% (−125, −46%), indicating increasing N availability while decreasing potential N loss. …”

Percentages of inhibition of biofilm formation and eradication of synthesized 1,2,3,5-tetrazine derivatives. by Jean Paul Dzoyem (6424445)

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Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV by Henryk Majczyński (830716)

“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT₂ (Cyproheptadine; Cypr), 5-HT_2A neutral antagonist (Volinanserin; Volin), 5-HT_2C neutral antagonist (SB 242084), and 5-HT_2B/2C inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”

Heterogeneous distribution of 5-HTR subtypes as measured by PET. by Yukiko Hori (299784)

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Table_1_FMT intervention decreases urine 5-HIAA levels: a randomized double-blind controlled study.DOCX by Lihong Wang (14991)

DataSheet1_Lorcaserin Inhibit Glucose-Stimulated Insulin Secretion and Calcium Influx in Murine Pancreatic Islets.docx by Muhan Jing (11651452)

“…Lorcaserin can restrain patients’ appetite and improve insulin sensitivity and hyperinsulinemia mainly through activating 5-HT_2CR in the hypothalamus. It is known that the mCPP, a kind of 5-HT_2CR agonist, decreases plasma insulin concentration in mice and previous research in our laboratory found that mCPP inhibited glucose-stimulated insulin secretion (GSIS) by activating 5-HT_2CR on the β cells. …”

Effect of NAC on decreased MYH expression caused by arecoline in C2C12 cells. by Yi-Xuan Li (6633845)

Effect of NAC on decreased myogenin expression caused by arecoline in C2C12 cells. by Yi-Xuan Li (6633845)

The apparent Ca²⁺ affinity of release is decreased by hydrophobic mutations. by Matthew R. Bowers (8423115)

Two hypothesized models for C period decrease as growth rate increases. by Sara Sanders (4163479)