Image3_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

eIF5a is up-regulated in unruptured AAAs and decreased in ruptured AAAs. by Dong Ma (584680)

Subjects:

Image 5_Using sodium glycodeoxycholate to develop a temporary infant-like gut barrier model, in vitro.pdf by Francesca Bietto (21511316)

“…</p>Methods<p>This study aimed to develop an in vitro model of the infant gut barrier treating Caco-2/HT29-MTX with 0.5, 0.8, and 1 mM sodium glycodeoxycholate (GDC).…”

PNs, ORNs and LNs response to a short (50 ms) pulse, similar results of Fig 4. by Mario Pannunzi (553941)

Developmental change in 5-HT_1A binding in known cause of death controls (predischarge and postdischarge combined). by Hannah C. Kinney (10280975)

“…Binding in these nuclei are visually (top row) and quantitatively (bottom row) decreasing with PC age, the latter shown with plots of 5-HT_1A binding vs PC age. …”

The minimum inhibitory concentrations (µg/mL) and the minimum bactericidal concentrations (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives. by Jean Paul Dzoyem (6424445)

Subjects:

Proteins in thyroid tissue with differential expression levels above or below 1.5 for all activity groups (0.5, 5, 50 and 500 kBq) (totally 133 proteins). by Malin Larsson (1616557)

“…Eight of these proteins were present in all four groups (ARF3, DLD, IKBKB, KTR4, NONO, RAB6A, RPN2 and SLC25A5). For the majority of proteins, the expression levels were ether increased or decreased for all activity levels.…”

Synthesis, Radiolabeling, and in Vitro and in Vivo Evaluation of [¹⁸F]ENL30: A Potential PET Radiotracer for the 5‑HT₇ Receptor by Elina Tampio L’Estrade (6619937)

“…The 5-HT₇ receptor (5-HT₇R) is involved in a broad range of physiological conditions and disorders. …”

Comparison of the ISIs that caused 0%, 50% and 100% decreases in response magnitudes (AI spikes, AI fEPSP and MGBv spikes) to succeeding tone. by Colin Xiong (9182695)

5-HT2A and Foxo are required in R2/R4 neurons to mediate the effects of death perception on lifespan. by Christi M. Gendron (14200157)

“…<p>Knock-down of <i>5-HT2A</i> mRNA expression in R2 alone (A), in R4d alone (B), or in R2/R4 inhibited lifespan differences due to death perception. …”

Glial 5-HT_2a receptors are necessary and rate limiting for experience-dependent synaptic glomeruli pruning. by Vanessa Kay Miller (19775496)

“…The Or42a OSN innervation volume with glial <i>5-HT</i>_<i>2A</i><i>R</i> OE is very significantly decreased in comparison to the control EB condition (<i>p</i> = 4.64 × 10⁻¹⁰). …”

Percentage of violacein production in <i>Chromobacterium violaceum</i> by the most active synthesized 1,2,3,5-tetrazine derivatives (4a, 4b and 4c). by Jean Paul Dzoyem (6424445)

Subjects:

Shoot-to-root translocation of GmNN1/FT2a regulates soybean nodulation. by Xinxin Li (281237)

Diallyl Trisulfide, an Active Substance from Garlic, Inhibits Female Oviposition by Decreasing the Expression of the <i>OCT</i> Gene, which is Highly Expressed in the Spermathecal... by Wen-Han Yan (20539256)

“…Conversely, triacylglycerol (TG) decreased significantly. The expression of the 5<i>-HT</i> 2<i>A</i> receptor gene, which is highly expressed in the abdomen, was significantly decreased. …”

Diallyl Trisulfide, an Active Substance from Garlic, Inhibits Female Oviposition by Decreasing the Expression of the <i>OCT</i> Gene, which is Highly Expressed in the Spermathecal... by Wen-Han Yan (20539256)

“…Conversely, triacylglycerol (TG) decreased significantly. The expression of the 5<i>-HT</i> 2<i>A</i> receptor gene, which is highly expressed in the abdomen, was significantly decreased. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”

Effects of SNPs on the Protein Stability, Increasing or Decreasing. by Mirza Jawad Ul Hasnain (8351388)

HT22 viability and LDH release. by Lu Li (14069)

Image4_The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice.JPEG by Vladimir M. Pogorelov (133492)

“…Despite these benefits, the hallucinogenic actions of these drugs at the serotonin 2A receptor (5-HT2AR) limit their clinical use in diverse settings. …”