Search alternatives:
ht decrease » _ decrease (Expand Search), nn decrease (Expand Search), step decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), mean decrease (Expand Search)
ng decrease » nn decrease (Expand Search), _ decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
ht decrease » _ decrease (Expand Search), nn decrease (Expand Search), step decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), mean decrease (Expand Search)
ng decrease » nn decrease (Expand Search), _ decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
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Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs
Published 2022“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs
Published 2022“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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5-HT inhibits <i>P</i>. <i>berghei</i> infection in mosquitoes.
Published 2024“…The purple boxes represent the metabolites of the indole pathway, the blue boxes represent the metabolites of the 5-HT pathway, and the tan boxes represent the metabolites of the kynurenine pathway. …”
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Additional Analysis of visually induced calcium transients in Fig 5.
Published 2020“…<p>Visually induced calcium transients were recorded in flies expressing L2-split-GAL4>GCaMP6f as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g005" target="_blank">Fig 5</a>. …”
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NgR1 KO mice exhibited an increase in excitatory synapses and a decrease in inhibitory synapses, indicating an imbalance of synaptic transmission.
Published 2025“…The inhibitory synaptic density of NgR1 mice showed a significant decrease when compared to WT mice (***P < 0.001). …”