Showing 81 - 100 results of 148,689 for search '(( 5 ht decrease ) OR ( 10 ((((nm decrease) OR (mean decrease))) OR (a decrease)) ))', query time: 0.85s Refine Results
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    Treatment with pan-PKC inhibitor Gö-6983 resulted in a non-significant decrease in <i>GRK6</i> promoter activity. by Maike Stegen (8578665)

    Published 2021
    “…Promoter activity was decreased after inhibition of PKC. (B) Combined treatment with 10 nM Gö-6983 + 10 nM PMA in comparison to a control with 10 nM PMA also led to a reduction in <i>GRK6</i> promoter activity. …”
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    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
  16. 96

    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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