PI3K-C2α knockdown decreases autophagy and maturation of endocytic vesicles by Nathan M. Merrill (4437367)

Schematic representation of possible intracellular 5-HT signaling pathways in chondrocytes. by Ayaka Hori (4597795)

“…Then, the phosphorylated ERK1/2 level is increased through both activation of PKCε and PKCζ; as a result, CCN2 production is decreased. Furthermore, independent of PKC, 5-HT may transmit a certain unknown signal to JNK, which also inhibits the CCN2 production in chondrocytes.…”

Phenotype and molecular identification of <i>GmNN1/FT2a</i> in stable transgenic soybean plants. by Xinxin Li (281237)

Human Embryonic Stem Cell-Derived Mesenchymal Stromal Cells Decrease the Development of Severe Experimental Autoimmune Uveitis in B10.RIII Mice by Yu Qin (166316)

“…<p><i>Purpose</i>: We investigated the effect of exogenously administered human embryonic stem cell-derived mesenchymal stromal cells (hESC-MSCs) in experimental autoimmune uveitis (EAU) in B10.RIII mice, a murine model of severe uveitis.…”

Fli-1 directly activates miR-17-92 promoter and contributes to miR-17 and miR-20a expression in NN10#5 cells. by Samer Kayali (133888)

“…<p>A: NN10#5 cells have been cultured for two days in absence or presence of Dox used to induce Fli-1 knock-down before analysis. …”

5.HT_1A binding difference between known cause of death (KCOD) controls and SIDS. by Hannah C. Kinney (10280975)

“…When SIDS is compared to all KCOD controls, the HG, NTS, and MAO show a significant mean difference in 5-HT_1A receptor binding. Data include the combined South Africa and Northern Plains cohorts.…”

The <i>AtTIFY10a/b</i> knockout mutant <i>Arabidopsis</i> showed decreased alkaline tolerance at the seed germination stage. by Dan Zhu (139675)

Transcriptomic Analysis Shows Decreased Cortical Expression of NR4A1, NR4A2 and RXRB in Schizophrenia and Provides Evidence for Nuclear Receptor Dysregulation by Susan M. Corley (3590576)

Effect of 2% HQ, 0.05% INN and 0.1% TAC on hippocampal 5-HT level and 5-HT_{1A /1B} receptor expression. by Huali Wu (349567)

“…Scale bar = 100μm. (E) The expression of 5-HT_1A and 5-HT_1B receptors was decreased in INN and TAC-treated mice. …”

The distributions of the end-simulation adolescence-limited proportion when (a) <i>k</i> is increased or decreased by 50%, (b) <i>c</i> is increased or decreased by 50%, (c) <i>γ</... by Jia Ning Leaw (752775)

Flibanserin’s neuroprotective effects are 5-HT_1A receptor-mediated. by Aaron S. Coyner (2889722)

“…The gray area indicates ± 2 SD of the naïve averaged data. (<b>A ii, A iii</b>) Receptor plus thicknesses, with each dot representing average right and left eye thickness from one mouse, demonstrate that both pre-treatment of BALB/c mice with WAY 100635 prior to a flibanserin injection (10 mg/kg WAY + 6 mg/kg Flibanserin, <i>green</i>) and a flibanserin injection in 5-HT_1A knockout mice (5-HT1A KO + 6 mg/kg Flibanserin, <i>red</i>) significantly reduces the observed neuroprotective effects provided by a single 6 mg/kg dose of flibanserin (6 mg/kg Flibanserin, <i>blue</i>) in the <b>(A ii)</b> temporal quadrant and the <b>(A iii)</b> nasal quadrant. …”

Data_Sheet_1_Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer’s Disease Consistent With Cerebral Pantothenate Deficiency.PDF by Crystal Sang (12856397)

Effects of gravity changes on gene expression of BDNF and serotonin receptors in the mouse brain by Chihiro Ishikawa (4093267)

“…BDNF expression was decreased in the ventral hippocampus and hypothalamus, whereas increased in the cerebellum. 5-HT1BR expression was decreased in the cerebellum, whereas increased in the ventral hippocampus and caudate putamen. …”

Design, Synthesis, and Biological Evaluation of New Peripheral 5HT_2A Antagonists for Nonalcoholic Fatty Liver Disease by Minhee Kim (1592440)

“…Recent findings suggest that peripheral serotonin (5-hydroxytryptamine, 5HT) regulates energy homeostasis, including hepatic lipid metabolism. …”

Downstream signaling pathways of the Htr2b receptor in the mammary gland are altered by serotonin deficiency. by Jimena Laporta (383836)

DataSheet1_Pharmacological inhibition of receptor protein tyrosine phosphatase β/ζ decreases Aβ plaques and neuroinflammation in the hippocampus of APP/PS1 mice.docx by Teresa Fontán-Baselga (20392470)

“…In addition, we observed a significant decrease in the number and size of astrocytes in both sexes and in the number of microglial cells in a sex-dependent manner. …”

<i>WNT10A</i>^–/–KO skin wound showing reduced fibrosis/fibrogenesis associated with the decreased expression of stromagenesis-related genes. by Ke-Yong Wang (234594)

Mechanical acupuncture by MAI decreases cocaine-induced locomotor activity in a stimulus time-dependent manner. by Seol Ah Kim (486416)

Top 10 pathways with the lowest p-value. by Rizka Fatriani (17485787)

A Two-Year Randomized Trial of Interventions to Decrease Stress Hormone Vasopressin Production in Patients with Meniere’s Disease—A Pilot Study by Tadashi Kitahara (702040)