Data_Sheet_2_Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala.ZIP by Magdalena T. Weidner (6689105)

“…In Tph2^-/- mice, brain 5-HT deficiency profoundly affected socio-emotional behaviors, i.e., decreased avoidance of the aversive open arms in the elevated plus-maze (EPM) as well as decreased prosocial and increased rule breaking behavior in the resident-intruder test when compared to their wildtype littermates. …”

Data_Sheet_3_Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala.ZIP by Magdalena T. Weidner (6689105)

“…In Tph2^-/- mice, brain 5-HT deficiency profoundly affected socio-emotional behaviors, i.e., decreased avoidance of the aversive open arms in the elevated plus-maze (EPM) as well as decreased prosocial and increased rule breaking behavior in the resident-intruder test when compared to their wildtype littermates. …”

Activation of Wnt and Smad/ZEB signaling by EGTA+EGF+FGF-1 but not p120 knockdown. by Hung-Chi Chen (165980)

“…<p>ARPE-19 cells cultured to day 7 post-confluence were treated with PBS or 1 mM EGTA plus 10 ng/ml EGF and 20 ng/ml FGF-2 for 1 day with or without 5 ng/ml XAV939, or transfected with 100 nM scRNA or p120 siRNA for 2 days. …”

Relevance of BMP4 signaling in proliferation and viability in ALL-MSCs. by Ángeles Vicente López (506074)

“…Note the low proliferation in cultures treated with high doses of BMP4 (100 ng/mL) and its similarity to that found in non-treated cultures of ALL-MSC-Diagnosis endogenously producing high amounts of the morphogen. …”

Supplementar material of the manuscript  The Effects of Lipoic Acid on Yolk Nutrient Utilization, Energy Metabolism, and Redox Balance over Time in <em>Artemia</em> sp.  by Juan Rafael Buitrago Ramírez (6244172)

“…ETS activity was positively regulated by the addition of LA, with the most significant effects at concentrations of 5.0 and 10.0 µM at 12 and 24 h. For ETS activity, treatments with LA presented the highest values at 24 h, a period when ROS production decreased significantly, for the treatment with 10.0 µM. …”

Figure 2 from Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in <i>EGFR</i>- and <i>KRAS</i>-Mutant Lung Cancer by Xiaoxiao Sun (20589448)

“…Doxycycline (Dox, 100 ng/mL) was administered concurrently with targeted drugs to ensure PRMT1 knockdown. …”

Supporting main Fig 2. by Jyoti Tanwar (2230597)

“…<p><b>MCU positively regulates melanogenesis while MCUb negatively controls melanogenesis. (A)</b> Quantitation of resting mitochondrial Ca²⁺ with CEPIA2mt in siNT control and siMCUb B16 cells stimulated with 100 μm histamine. …”

Long term follow up of biomarkers of podocyte damage and renal function in patients with and without preeclampsia by Ylbe Palacios de Franco (5254832)

“…In preeclampsia patients, urinary podocalyxin decreased from 97.5 ng/mg [64.9, 318.4] during pregnancy to 37.1 ng/mg within one week post-partum [21.3, 100.4] p = 0.05 and 4.34 ng/mg [2.69, 8.99] three years after, p = 0.003. …”

Long term follow up of biomarkers of podocyte damage and renal function in patients with and without preeclampsia by Ylbe Palacios de Franco (5254832)

“…In preeclampsia patients, urinary podocalyxin decreased from 97.5 ng/mg [64.9, 318.4] during pregnancy to 37.1 ng/mg within one week post-partum [21.3, 100.4] p = 0.05 and 4.34 ng/mg [2.69, 8.99] three years after, p = 0.003. …”

CPZ pretreatment inhibits cleaved caspase-3 expression in rat brains after ethanol exposure. by Jing Wu (54032)

“…All three doses of CPZ result in a significant decrease of the cleaved caspase-3 levels compared with ethanol group.…”

DataSheet_1_Intestinal Microbiota Mediates High-Fructose and High-Fat Diets to Induce Chronic Intestinal Inflammation.docx by Rong Tan (18617)

“…Meanwhile, the content of 5-hydroxytryptamine (5-HT) was significantly decreased, which might cause constipation by reducing intestinal peristalsis. …”

File S1 - <i>FGFR2</i> Is Amplified in the NCI-H716 Colorectal Cancer Cell Line and Is Required for Growth and Survival by Anjili Mathur (163690)

“…</b> Lysates were processed as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0098515#pone-0098515-g001" target="_blank">Figure 1A</a>. “+” indicates addition of 50 ng/ml FGF2 for 15 minutes. …”

TGFβ signaling promotes NDR1 turnover. by Isabelle Pot (427025)

“…Data are presented as the mean+SEM (n = 4) of percent decrease in protein abundance of NDR1 in NMuMG cells in response to TGFβ. …”

Supporting data for "Excess mortality during the COVID-19 pandemic in Hong Kong and South Korea" by Shuqi Xu (12992556)

“…Mortality from influenza and pneumonia was estimated to have a statistically significant increase in HK but a decrease in SK probability due to different coding practices. …”

Data Sheet 2_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Data Sheet 1_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Inhibition of Enterovirus 71 (EV-71) Infections by a Novel Antiviral Peptide Derived from EV-71 Capsid Protein VP1 by Chee Wah Tan (167218)

“…Substitutions of arginine and lysine residues with alanine in the SP40 peptide at positions R3A, R4A, K5A and R13A were found to significantly decrease antiviral activities, implying the importance of positively charged amino acids for the antiviral activities. …”

Role of SIRT-2 in the endotoxin tolerant RAW cells. by Xianfeng Wang (120153)

“…<p><u>A: RAW cells undergo endotoxin tolerance as early as 4h after LPS stimulation:</u> To study endotoxin tolerance in RAW cells, we stimulated cells with LPS (100ng/ml) and re-stimulated with another LPS challenge (100ng/ml) at 0, 4, 6, 8, and 24 hour time points for four hour. …”

Hepatoprotective and antioxidant effect of ellagitannins and galloyl esters isolated from <i>Melaleuca styphelioides</i> on carbon tetrachloride-induced hepatotoxicity in HepG2 cel... by Eman Al-Sayed (2934060)

“…(Myrtaceae) showed a significant hepatoprotective effect in a CCl₄-induced toxicity model in mice. …”

<i>Pf</i>PKA-mediated phosphorylation contributes to immature GIE stiffness. by Ghania Ramdani (676819)

“…The pHL-<i>pfpka-r</i> clone was pre-incubated 15 min at 37°C with 100μM 8Br-cAMP. Error bars denote the standard error of the mean. …”