Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Flow cytometry data of AX4 cells transfected with the P2A plasmid and selected with 100 μg/ml hygromycin. by Xinwen Zhu (14709669)

Analysis of tumour vasculature with the addition of more HT groups. by Deepa Sharma (278210)

Glia-targeted 5-HT_2A receptor expression in adults reopens experience-dependent synaptic glomeruli pruning. by Vanessa Kay Miller (19775496)

“…There is a significant decrease in the Or42a OSN innervation volume with glial-targeted <i>Gal80</i>^<i>ts</i><i>-5-HT</i>_<i>2A</i><i>R</i> OE at 28°C (<i>n</i> = 20/condition, <i>p</i> = 1.00 × 10⁻¹⁵). …”

Normalized pressure pain thresholds (PPTs) (mean ± SEM) at start, middle, end and 5 minutes after a standardized tourniquet test. by Jeanette Tour (10790855)

IFNγ enhances the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> uptake by the human U-87 MG astroglioma cells. by Glaucia Vilar-Pereira (686134)

Fx treatment abrogates the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> infection of human U-87 MG astroglioma cells. by Glaucia Vilar-Pereira (686134)

Additional behavioral patterns in the 5€, 100€, and 1000€ treatments. by Pablo Brañas-Garza (336425)

Decreased membrane localization of myrGFP in <i>ACBD6</i>-deficient cells. by Eric Soupene (64584)

STAT6 siRNA sequences 1 and 4 significantly reduce cell proliferation. by Carmen Salguero-Aranda (6690044)

STAT6 siRNA sequences 1 and 4 significantly block STAT6 expression. by Carmen Salguero-Aranda (6690044)

STAT6 siRNA sequences 1 and 4 induce apoptosis. by Carmen Salguero-Aranda (6690044)

JetPEI transfection reagent works for transfecting efficiently STAT6 siRNAs <i>in vitro</i>. by Carmen Salguero-Aranda (6690044)

MCF-7 cells were treated with 0, 10, or 20 μM of Peptide 1 or Peptide 2 for 48h. by Deepu Dowarha (5673440)

Subjects:

S100A1 complete sequence indicating highlighted region selected for peptide construction, attaching it to HIV-TAT peptide forming Peptide 1 and its scramble arrangement in Peptide... by Deepu Dowarha (5673440)

Subjects:

Fig 9 - by Deepu Dowarha (5673440)

Subjects:

The p53-MDM2 interaction was monitored via fluorescence spectroscopy. by Deepu Dowarha (5673440)

Subjects:

Analysis of WST-1 assay. by Deepu Dowarha (5673440)

Subjects:

The ¹H−¹⁵N HSQC spectra overlay of free ¹⁵N p53 (1–73) (red) and in complex with unlabelled S100A1 (yellow). by Deepu Dowarha (5673440)

Subjects:

Fig 16 - by Deepu Dowarha (5673440)

Subjects: