Chordoma preclinical models are insensitive to BAF complex inhibitor FHD-286, alone or in combination with gemcitabine by Chordoma Foundation (4391989)

“…A panel of 4 chordoma cell lines were seeded in a white-walled 96-well plate so that at the start of treatment, 36 hours after plating, the confluence was 15%. …”

Self-limiting of the gTLR9 signaling by <i>gTlr9</i> alternative splicing. by Frank Fang-Yao Lee (2210863)

“…DRB pre-treatment (0 h) led to slight increase of <i>9A</i> (<b>B</b>) and decrease of <i>9B</i> (<b>C</b>) (Cf. the two gray bars vs. white and black bars). …”

Feijoa F3 does not activate autophagy or inhibit NF-κB activity in autophagy defective HCT116 cells. by Noha Ahmed Nasef (760610)

“…A percentage of greater than 100 shows increased inflammatory response in the presence of the ligand when compared to media (no treatment); and a percentage of less than 100 suggests a decrease in the inflammatory response in the presence of the ligand when compared to media (no treatment) meaning that a condition has inhibited NF-κB signaling. …”

Image_2_Focal non-invasive deep-brain stimulation with temporal interference for the suppression of epileptic biomarkers.JPEG by Emma Acerbo (10933287)

“…The most prominent alterations concern high-frequency oscillations (HFOs), namely an increase in ripples, a reduction in pathological Fast Ripples (FRs), and a decrease in pathological interictal epileptiform discharges (IEDs).…”

Image_1_Focal non-invasive deep-brain stimulation with temporal interference for the suppression of epileptic biomarkers.JPEG by Emma Acerbo (10933287)

“…The most prominent alterations concern high-frequency oscillations (HFOs), namely an increase in ripples, a reduction in pathological Fast Ripples (FRs), and a decrease in pathological interictal epileptiform discharges (IEDs).…”

Comparative proteomic analysis of the moderately resistant and susceptible peanut cultivars during infestation by <i>Cylindrocladium parasiticum</i> by Xinyu Chen (47670)

“…However, MAPK signal pathway was more pronounced in moderately resistant peanut cultivar T09. We also observed an increase of CYP73A100 involved in phenylpropanoid and flavonoid biosynthesis pathways in susceptible peanut ecotype P562, while decrease in moderately resistant interaction. …”

DataSheet_1_Nitrogen Enrichment Reduces the Diversity of Bacteria and Alters Their Nutrient Strategies in Intertidal Zones.pdf by Yuan-Feng Xu (13037058)

“…To address this gap, we conducted a two-month mesocosm experiment using six targeted concentrations of total N. …”

Data_Sheet_1_Development of BacMam Induced Hepatitis E Virus Replication Model in Hepatoma Cells to Study the Polyprotein Processing.ZIP by Manjeet Kumar (712166)

“…A 20% decrease in the replicative forms of RNA could be seen in presence of 100 μM Ribavirin after 48 h of treatment. …”

Characterization of <em>Abcc4</em> Gene Amplification in Stepwise-Selected Mouse J774 Macrophages Resistant to the Topoisomerase II Inhibitor Ciprofloxacin by Béatrice Marquez (193669)

“…Abcc4 expression progressively increased upon selection rounds, with exponential changes observed between cells exposed to 150 and 200 µM of ciprofloxacin, accompanied by a commensurate decrease in ciprofloxacin accumulation. …”

Selective loss of macrophage subpopulations in lymphoid tissue of <i>Csf1rko</i> rats. by Dylan Carter-Cusack (20624041)

“…Positive logFC indicates an increase in expression in <i>Csf1rko</i> animals, while negative logFC indicates a decrease in expression in <i>Csf1rko</i> animals. …”

Effect of 3BrP on morphology, cell number, viability, proliferation and pluripotency. by Ana Sofia Rodrigues (491559)

“…Cells stained green were counted as live, while PI positive cells were counted as dead. 100 cells were counted per condition for a total of n = 8 independent experiments, results are expressed as means ± SEM for 30 experiments. …”

Deletion of RBPJK enhances cell spontaneous differentiation in regular MSC culture. by Xifu Shang (784529)

“…<p>Mesenchymal stem cells were infected with Control shRNA(Co) or RBPJK shRNA (shRBPJK) lentivirus before being harvested for alkaline phosphatase (ALP) staining, western blot, RT-PCR analysis and BrdU ELISA. (A) Western Blot showed a significant decrease of RBPJK protein expression at day 3 and 14 following shRBPJK lentiviral infection. …”

Myelin and myelin proteins are marginally reduced in the brain of <i>Syn1Cre; Galc flox/−</i>. by Conlan Kreher (13001753)

“…Scale bar = 100 μm. (<b>E</b>) Quantification of PLP level, measured by averaged integrated signal intensity, reveals a trend of reduction in the mutant brain. …”

Figure 4, supplementary figure 6 by Kristen Pleil (11084931)

“…</b>a) Proportion of responder categories during 10-minute E2 wash on across E2 doses (0.01, 1, 10, 100, 1000 nM) for frequency (top) and amplitude (bottom). b) Raw average frequency (top) and amplitude (bottom) during baseline, E2 wash on, and washout for each cell. c) Maximum % change from baseline for cells categorized as increased and decreased during E2 wash on for frequency (top) and amplitude (bottom). …”

Competitive tuning: Competition's role in setting the frequency-dependence of Ca²⁺-dependent proteins by Daniel R. Romano (4574287)

“…In this work, we view Ca²⁺/CaM as a limiting resource in the signal transduction pathway owing to its low abundance relative to its binding partners. …”

Changes in nuclear disorder strength (L_d) following VPA treatment. by Yolanda Stypula-Cyrus (416086)

“…<p><b>A)</b> Representative pseudocolor PWS images from nuclei of HT-29 and CSK constructs untreated or treated with 0.5 mM VPA. …”

Cation Vacancies in NiFe2O4 During Heat Treatments at High Temperatures: Structural, Morphological and Magnetic Characterization by Harrison Salazar-Tamayo (8183697)

“…On the other hand, Mössbauer spectrometry showed that there is a decrease in the subspectral areas ratio for Fe3+ cations at tetrahedral (A) and octahedral [B] sites, AA/AB, with the increase of the temperature. …”

Supplementary Material for: Real-world effectiveness of piperacillin/tazobactam with and without linezolid for spontaneous bacterial peritonitis by Quickert S. (12023954)

“…Treatment failure, defined as the need to escalate antibiotic therapy due to in vitro resistance, lack of neutrophil decrease in ascitic fluid, or clinical decision, and 30-day survival were retrospectively assessed. …”

Supplementary Material for: Real-world effectiveness of piperacillin/tazobactam with and without linezolid for spontaneous bacterial peritonitis by Quickert S. (12023954)

“…Treatment failure, defined as the need to escalate antibiotic therapy due to in vitro resistance, lack of neutrophil decrease in ascitic fluid, or clinical decision, and 30-day survival were retrospectively assessed. …”

Table_1_Intratracheal inoculation results in Brucella-associated reproductive disease in male mouse and guinea pig models of infection.DOCX by Martha E. Hensel (6425414)

“…Vaccination resulted in a significant reduction in colonization in the mouse, but this could not be correlated with a decrease in inflammation. …”