Modelling results of the study "Doomed descent? How fast sulphate signals diffuse in the EPICA Dome C ice column" by Felix S L Ng (8012813)

“…Inversion for EDC sulphate reveals a rapid decrease in <i>D</i> through the firn layer – from ≈ 10^–6 m² yr^–1 at the surface to ≈ 1.7 ´ 10^–8 m² yr^–1 at the firn-ice transition (≈ 100 m depth, ≈ 2.5 ka), followed by a gradual decline to ≈ 10^–10m² yr^–1 through 100–2700 m (2.5–390 ka). …”

Point-of-care testing for <i>Toxoplasma gondii</i> IgG/IgM using <i>Toxoplasma</i> ICT IgG-IgM test with sera from the United States and implications for developing countries by Ian J. Begeman (4172935)

“…</p><p>Results</p><p>We found that this new <i>Toxoplasma</i> ICT IgG-IgM POC test was highly sensitive (100%) and specific (100%) for distinguishing IgG/IgM-positive from negative sera. …”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…However, as improved detection and increasing exposure to carcinogens has led to higher rates of cancer incidence, clinicians and researchers have not balanced that increase with a similar decrease in cancer mortality rates. This mismatch highlights a clear and urgent need for increasingly potent and selective methods with which to detect and treat cancers at their earliest stages.Nanotechnology, the use of materials with structural features ranging from 1 to 100 nm in size, has dramatically altered the design, use, and delivery of cancer diagnostic and therapeutic agents. …”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…However, as improved detection and increasing exposure to carcinogens has led to higher rates of cancer incidence, clinicians and researchers have not balanced that increase with a similar decrease in cancer mortality rates. This mismatch highlights a clear and urgent need for increasingly potent and selective methods with which to detect and treat cancers at their earliest stages.Nanotechnology, the use of materials with structural features ranging from 1 to 100 nm in size, has dramatically altered the design, use, and delivery of cancer diagnostic and therapeutic agents. …”

Video2_TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.mp4 by Zi-Meng Xia (14847547)

“…Background<p>Tissue inhibitor of metalloproteinase 3 (TIMP3) was recently demonstrated capable to regulate some gene expression in a myocardial infarction model. Here we aim to explore the gene expression profile in TIMP3-treated cardiomyocytes and related potential cardiovascular functions.…”

Datasheet1_TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.pdf by Zi-Meng Xia (14847547)

“…Background<p>Tissue inhibitor of metalloproteinase 3 (TIMP3) was recently demonstrated capable to regulate some gene expression in a myocardial infarction model. Here we aim to explore the gene expression profile in TIMP3-treated cardiomyocytes and related potential cardiovascular functions.…”

Video1_TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.mp4 by Zi-Meng Xia (14847547)

“…Background<p>Tissue inhibitor of metalloproteinase 3 (TIMP3) was recently demonstrated capable to regulate some gene expression in a myocardial infarction model. Here we aim to explore the gene expression profile in TIMP3-treated cardiomyocytes and related potential cardiovascular functions.…”

Feijoa F3 activates autophagy and inhibits NF-κB activity in HCT15 cells. by Noha Ahmed Nasef (760610)

“…A percentage of greater than 100 shows increased inflammatory response in the presence of the ligand when compared to media (no treatment); and a percentage of less than one suggests a decrease in the inflammatory response in the presence of the ligand when compared to media (no treatment) meaning that a condition has inhibited NF-κB signaling. …”

Uniform downscaling of postsynaptic AMPA receptors across the dendritic tree in primary hippocampal cultures. by Mathieu Letellier (6803699)

“…(B) Representative EPSC trace evoked by a pair of brief depolarizations (+100 mV, 50-ms interval) of the presynaptic neuron. …”

Effect of hypotonic stress and elevated K⁺ on the ECS diffusion parameters in α-syn +/+ and α-syn −/− mice <i>in vitro</i>. by Lesia Dmytrenko (431060)

“…The mean values of the maximum change during application correspond to the time-point of the maximum decrease of α (i.e., the 25^th min in H-50 and H-100 and the 30^th min in 10 mM K⁺); the values for washout correspond to the data point at the 90^th min. …”

Treatment Satisfaction and Well-Being in Patients with Myopic Choroidal Neovascularization Treated with Ranibizumab in the REPAIR Study by Winfried M. Amoaku (748780)

“…Treatment satisfaction significantly increased over the study period (<i>p</i> = 0.0001). Mean MacTSQ scores increased by 9.7 and 10.0 in patients treated in their WSE and BSE, respectively. …”

BV and GSK3β siRNA modulate the levels of cytokines in the supernatants of cultured splenocytes. by Ran Fu (434520)

“…<p>Both BV (100 μg/mL) and GSK3β siRNA (100 pmol/mL) were shown to significantly decrease the levels of IL-4, but increase the levels of IL-10 and TGF-β1 in the supernatants of cultured splenocytes. …”

Mechanosensitive response in <i>pain</i> loss of function individuals. by Sébastien Sénatore (80383)

“…In the three mutants and in the RNAi line, a significant decrease is observed following <i>painless</i> knock-down. …”

Data_Sheet_1_Characterization of Fructan Metabolism During Jerusalem Artichoke (Helianthus tuberosus L.) Germination.PDF by Jiao Jiao (297582)

“…Ht1-SST (sucrose:sucrose 1-fructosyl transferase, inulin synthesis initiator), and Ht1-FFT (fructan:fructan 1-fructosyl transferase, inulin elongator) expression generally decreased in indoor-grown T. …”

Data_Sheet_1_Polygenic Risk Score for Early Prediction of Sepsis Risk in the Polytrauma Screening Cohort.docx by Hongxiang Lu (2947089)

“…Genetic variants with mean decrease accuracy (MDA) > 1.0 by random forest algorithms were selected to construct the multilocus wGRS. …”

Image_1_Polygenic Risk Score for Early Prediction of Sepsis Risk in the Polytrauma Screening Cohort.TIF by Hongxiang Lu (2947089)

“…Genetic variants with mean decrease accuracy (MDA) > 1.0 by random forest algorithms were selected to construct the multilocus wGRS. …”

GBE treatment improved mitochondrial capacity. by Virginie Rhein (243241)

“…Two-way ANOVA revealed also a significant effect of GBE (100 µg/ml; 24 h) on total O₂ consumption. …”

Table_1_Increasing Number of Individuals Receiving Hepatitis B nucleos(t)ide Analogs Therapy in Germany, 2008–2019.DOCX by Anna Maisa (263303)

“…Contrary to guideline recommendation, adefovir was still prescribed after 2011 for 1–5% of patients albeit with decreasing tendency. Prescriptions per 100,000 inhabitants were highest in Berlin and Hamburg.…”

Table_1_Increasing Number of Individuals Receiving Hepatitis B nucleos(t)ide Analogs Therapy in Germany, 2008–2019.DOCX by Anna Maisa (263303)

“…Contrary to guideline recommendation, adefovir was still prescribed after 2011 for 1–5% of patients albeit with decreasing tendency. Prescriptions per 100,000 inhabitants were highest in Berlin and Hamburg.…”

Low Socioeconomic Status Is Associated with Prolonged Times to Assessment and Treatment, Sepsis and Infectious Death in Pediatric Fever in El Salvador by Ronald Gavidia (141156)

“…Providing additional education to high-risk families and staying at a nearby guest house during periods of neutropenia may decrease sepsis and infectious mortality.…”