DataSheet_1_Human surfactant protein A inhibits SARS-CoV-2 infectivity and alleviates lung injury in a mouse infection model.pdf by Ikechukwu B. Jacob (18253300)

“…Pre-incubation of SARS-CoV-2 (Delta) with human SP-A inhibited virus binding and entry and reduced viral load in human lung epithelial cells, evidenced by the dose-dependent decrease in viral RNA, nucleocapsid protein (NP), and titer (p<0.01). …”

Targeted DNA demethylation in human cells by fusion of a plant 5-methylcytosine DNA glycosylase to a sequence-specific DNA binding domain by Jara Teresa Parrilla-Doblas (3825424)

“…In contrast, plants use specific DNA glycosylases that directly excise 5mC and initiate its substitution for unmethylated C in a base excision repair process. …”

Image_5_Upregulated IL-6 Indicates a Poor COVID-19 Prognosis: A Call for Tocilizumab and Convalescent Plasma Treatment.TIF by Jian Wu (41301)

“…As a stable indicator, the changes in IL-6 levels could indicate the inflammatory conditions during a viral infection. …”

DataSheet1_Identification of a Five-mRNA Signature as a Novel Potential Prognostic Biomarker for Glioblastoma by Integrative Analysis.DOCX by Huifang Xu (111603)

“…The model of the five-mRNA biomarker signature was successfully verified on a testing set and independent sets. …”

Audio_5_Changes in humpback whale song structure and complexity reveal a rapid evolution on a feeding ground in Northern Norway.wav by Saskia C. Tyarks (14239100)

Supplementary Material for: Novel digenic variants in COL4A4 and COL4A5 causing X-linked Alport Syndrome by Uedono H. (10917012)

“…The number of cases of digenic AS has increased, but the genotype-phenotype correlation of patient with digenic AS is still unclear. Here, we present a case of digenic AS with novel digenic missense variants in COL4A4 (c.827G>C, p.Gly276Ala) and COL4A5 (c.4369G>C, p.Gly1457Arg). …”

DataSheet_5_Hypothyroidism has a protective causal association with hepatocellular carcinoma: A two-sample Mendelian randomization study.pdf by Likui Lu (6631655)

“…There were no statistical indications of heterogeneity among instruments (P-het = 0.667). Across five MR methods, genetically predicted hypothyroidism shows a consistent correlation with HCC. …”

Supplementary Material for: Five-Year Therapy with Recombinant Human Insulin-Like Growth Factor-1 in a Patient with PAPP-A2 Deficiency by Muthuvel G. (14430801)

“…Introduction: The metalloproteinase pregnancy-associated plasma protein A2 (PAPP-A2) cleaves insulin-like growth factor (IGF) binding proteins 3 and 5 to release bioactive IGF-I from its ternary complex. …”

Expression of selected genes at PG and PV stages in <i>bmp15</i> mutant. by Yue Zhai (3141960)

Competitive Arsenate and Phosphate Adsorption on Ferrihydrite as Described by the CD-MUSIC Model by Jon Petter Gustafsson (1851535)

“…This causes a flatter adsorption isotherm for As­(V), which leads to a stronger As­(V) adsorption as the As­(V)-to-Fe ratio decreases, compared to that for PO₄.…”

Controlling Symmetry Breaking Charge Transfer in BODIPY Pairs by Laura Estergreen (1355682)

Identification of small molecules that inhibit viral M mRNA nuclear export and/or decrease viral M mRNA levels. by Matthew Esparza (8661219)

“…<p>(<b>A</b>) Representative images showing uninfected cells; cells infected with A/WSN/33 and pretreated with 0.5% DMSO (control), which show viral M mRNA exported into the cytoplasm, in red; and cells infected with A/WSN/33 pre-treated with 2.5 μM of the transcription inhibitor DRB (5,6-dichloro-1-β-D-ribofuranosylbenzimidazole). …”

Discovery of Oral AMP-Activated Protein Kinase Activators for Treating Hyperlipidemia by Mingchao Wang (450503)

“…A single dose of V1 (2000 mg) increased AMPK activation in human erythrocytes after 5 and 12 h of treatment. …”

Effects of hormone therapy and high-fat diet on microglia in female mice. by Amy Christensen (4062937)

“…In (H), white bar indicates NF + V (n = 7), grey indicates NF + HT (n = 5), black indicates HF + V (n = 8), and striped indicates HF + HT (n = 6). …”

Effects of Glu on PC synthesis in cultured lungs. by Xiao-Hong Li (286234)

Potential Interest in Circulating miR-BART17-5p As a Post-Treatment Biomarker for Prediction of Recurrence in Epstein-Barr Virus-Related Nasopharyngeal Carcinoma by Nobuyuki Hirai (3185838)

“…Post-treatment detection of miR-BART17-5p is a potential biomarker of a poor prognosis.…”

Therapeutic administration of mMSCs failed to decrease pulmonary inflammation or modify BAL inflammatory cell counts in experimental severe influenza. by Ilyse Darwish (446378)

Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response by N.N. Dang (6513023)

“…Filaggrin silencing also resulted in significant increases of IL-2, IL-4, IL-5, and IL-13 (P<0.05 or P<0.01), and significant decreases of IL-12p70 and IFN-γ (P<0.01) compared with cells in the Blank and NC groups. …”

Results of a dog’s detections after exposure to sweat samples from positive and negative people to SARS-CoV-2, together with the Ct values of the RT-qPCR test of each person partic... by Víctor M. Vidal-Martínez (18707335)

<i>In-vitro</i> reduced albumin from HD patients decrease the mRNA expression of inflammatory cytokines and adhesion molecules. by Faiga Magzal (4045067)