Molecular interactions of agonist and inverse agonist ligands at serotonin 5-HT_2C G protein-coupled receptors: computational ligand docking and molecular dynamics studie... by Tania C. Córdova-Sintjago (597380)

“…<div><p>To understand molecular determinants for ligand activation of the serotonin 5-HT_2C G protein-coupled receptor (GPCR), a drug target for obesity and neuropsychiatric disorders, a 5-HT_2C homology model was built according to an adrenergic β₂ GPCR (β₂AR) structure and validated using a 5-HT_2B GPCR crystal structure. …”

Absence of adaptive immunity decreases tumor cell damage in MDR1A deficiency. by Eva Maria Hennenberg (4234018)

FABP5 expression levels in brain microvessels from 2-, 8-, 12-, and 24-month-old mice. by Takuro Iwao (14636741)

Subjects:

Viral measurements do not predict off-ART rebound in d4 and d5 ART RMs. by Brandon F. Keele (7450001)

Pharmacologic blockade of 5LO decreases Aβ peptides levels and deposition in the 3×Tg mice via the γ-secretase pathway. by Jin Chu (358006)

The spike-in of synthetic hsa-lest-7a-5p miRNA decreases the Ct Values of extracted small RNA samples. by Marc Van Der Hofstadt (1423027)

Kcnk5b enhanced depolarization is required for enhanced fin bud growth. by Xiaowen Jiang (8291814)

Fig 5 - by Liang Cao (135383)

RSV decreased the Cav-1 and TGF-β expression in liver of rats fed high-fat diet. by Hui Yang (91136)

SERINC5 antagonism does not enhance viral replication in primary human CD4+ T cell cultures. by Dorota Kmiec (5646374)

Unusual [3+1] Cycloaddition of a Stable Silylene with a 2,3-Diazabuta-1,3-diene versus [4+1] Cycloaddition toward a Buta-1,3-diene by Yun Xiong (1403545)

“…The latter rearranges further to decrease ring strain, affording the corresponding 1-sila-4,5-diazacyclohex-3-ene <b>4</b>. …”

Image_5_Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination.tiff by Lydia Horndler (10503959)

Image_5_Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination.tiff by Lydia Horndler (10503959)

Microgliosis is decreased in the brains of 5XFAD/<i>LDLR</i>-/- and 5XFAD/<i>ApoE-/-LDLR</i>-/- mice. by Loukia Katsouri (348708)

“…Quantitation of Iba1 positive staining in the hippocampi and cortices showing a decrease in the 5XFAD/<i>LDL</i>-/- and 5XFAD/<i>ApoE</i>-/-<i>LDLR</i>-/- mice compared to the control mice. …”

Decrease of HLA-DR expression is more pronounced in severe cases. by Sanja Matic (9931091)

CEACAM levels decreased to <5% for CEACAM 1, 5 and 6 after shRNA knock down as shown in flow cytometry. by Florian Gebauer (318647)

Astrocytosis is decreased in the brains of 5XFAD/<i>LDLR</i>-/- and 5XFAD/<i>ApoE-/- LDLR</i>-/- mice. by Loukia Katsouri (348708)

“…Quantitation of GFAP positive staining in the hippocampi and cortices showing a decrease in the 5XFAD/<i>LDL</i>-/- and 5XFAD/<i>ApoE</i>-/-<i>LDLR</i>-/- mice compared to the control mice. …”

IgA is decreased in individual donor milk and is present in human milk-based fortifiers. by Christian Tamar (21100605)

Quantification of bacterial adhesion revealed a significant decrease in the adhesion of <i>S. aureus</i>, <i>S. epidermidis</i>, and <i>P. aeruginosa</i> on blotted corneas of mice treated with 0.5% bupivacaine (BUP) combined with topical (TOP) application, following subconjunctival injection (SCI) of CGRP, 24 hours before the final BUP treatment (day 14) and again one hour prior to the final bupivacaine injection on day 15. by Ananya Datta (19932144)

POm E-stimulation before whisker stimulus does not decrease cortical response magnitude and duration when PTX is applied in L1. by Carlos Castejon (2182382)