Showing 681 - 700 results of 99,522 for search '(( 5 ht decrease ) OR ( 5 ((((fold decrease) OR (point decrease))) OR (a decrease)) ))', query time: 1.44s Refine Results
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    Cycloheximide (CHX) treatment decreases production of rRNA transcripts by POLR1 and POLR3. by Martin Selinger (3195987)

    Published 2019
    “…<p>(A) DAOY cells were treated with CHX (100 μg/ml) for either 6 or 14 hours; for metabolic RNA labelling, 5-EU was added 2 hours before the sample collection. …”
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    Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen. by Pranjali Beri (14945400)

    Published 2023
    “…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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    Proposed model for the inhibitory effect of prolonged Htr2b activation on GSIS in MIN6 cells. by Luis Rodrigo Cataldo (3701206)

    Published 2017
    “…<p>MIN6 cells constitute a functional microserotoninergic system, with the ability to synthesis 5HT from its precursors (tryptophan or 5HTP), storage, degrade and release this monoamine. …”
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    Cell-targeted transgenic control of 5HT<sub>2A</sub>R levels in neurons and glia during the experience-dependent critical period. by Vanessa Kay Miller (19775496)

    Published 2024
    “…Two-way ANOVA with Tukey’s multiple comparison shows EB experience-dependent increase in 5HT<sub>2A</sub> receptor levels in both transgenic controls (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 5.38 × 10<sup>−10</sup>, <i>elav</i>-Gal4; <i>p</i> = 0.0205), a significant decrease in 5HT<sub>2A</sub> receptor levels in both RNAi conditions (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 4.63 × 10<sup>−10</sup>, <i>elav-</i>Gal4; <i>p</i> = 1.05 × 10<sup>−9</sup>), and a significant elevated EB response with glial <i>5HT</i><sub><i>2A</i></sub><i>R</i> OE (<i>n</i> = 10/condition, <i>p</i> = 2.36 × 10<sup>−9</sup>). …”
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