Showing 61 - 80 results of 99,522 for search '(( 5 ht decrease ) OR ( 5 ((((fold decrease) OR (point decrease))) OR (a decrease)) ))', query time: 1.36s Refine Results
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    Expression of 5-HT<sub>4(b)</sub>, 5-HT<sub>2A</sub>, 5-HT<sub>2B</sub> and 5-HTT mRNA in left ventricular myocardium. by Trond Brattelid (290970)

    Published 2013
    “…(A) 5-HT<sub>4(b)</sub> mRNA levels decreased with foetal and neonatal development and the level in adult myocardium was one tenth of that at day -3 but reappeared in HF; (B) 5-HT<sub>2A</sub> mRNA expression increased at birth (day 1), decreased during neonatal development and was unaltered in HF; (C) 5-HT<sub>2B</sub> mRNA expression was transiently increased at birth (day 1) compared to adult (day 113) and not changed in HF; (D) 5-HTT mRNA expression was lower in foetal hearts compared to neonatal, adult, Sham and HF which all showed a similar expression level. …”
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    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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    UVB irradiation decreased TM expression in HaCaT cells. by Huey-Chun Huang (429098)

    Published 2013
    “…<p>(A) HaCaT Cells were exposed to UVB irradiation in a dose-response (0, 1.5, 3, 4.5, 6 mJ/cm<sup>2</sup>) Cell viability was examined by trypan blue exclusion. …”
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    Decreased splicing efficiency in DENV infected cells. by Federico A. De Maio (3091644)

    Published 2016
    “…On the lower panel, increase or decrease retention of introns for each time point is shown.…”
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    Concentrations of 5-HT and 5-HIAA in brain tissue. by Thibault Renoir (348572)

    Published 2013
    “…Both 5-HT and 5-HIAA concentrations were decreased in the hippocampus (A/B), the cortex (C/D) and the striatum (E/F) in female HD mice when compared to WT animals. …”
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    GREAT GO analysis of WDR5 and MYCN overlapped ChIP-seq peaks with >2.5-fold decrease of WDR5 signal intensity after the silencing of <i>WDR5</i>. by Zhihui Liu (95891)

    Published 2024
    “…<p>GREAT GO analysis of WDR5 and MYCN overlapped ChIP-seq peaks with >2.5-fold decrease of WDR5 signal intensity after the silencing of <i>WDR5</i>.…”