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point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
ht decrease » _ decrease (Expand Search), nn decrease (Expand Search), we decrease (Expand Search)
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121
Additional Analysis of visually induced calcium transients in Fig 5.
Published 2020“…<p>Visually induced calcium transients were recorded in flies expressing L2-split-GAL4>GCaMP6f as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g005" target="_blank">Fig 5</a>. …”
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122
Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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123
Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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124
Fold decrease in virulence gene expression of <i>Salmonella in vivo</i> and <i>in vitro</i><sup>a</sup>.
Published 2014“…Values represent down-regulation (fold-decrease) of gene expression.</p>#<p>Value for each gene represents a significant difference (<i>P</i><0.05) between the treatment and control samples in the <i>in vitro</i> experiment. …”
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125
A homozygous point mutation in the <i>Mrps34</i> gene causes a decrease in the MRPS34 protein.
Published 2015“…The 5′- and 3′-untranslated regions are shown as grey boxes and the predicted mitochondrial targeting sequence is shown as a black box (predicted using MitoProtII, [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005089#pgen.1005089.ref040" target="_blank">40</a>]). …”
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Comparison of the effects of several 5-HT receptor antagonists on the plasma concentrations of metabolites and insulin, following 5-HT injection in sheep and mice.
Published 2014“…</p>b<p>5-HT: serotonin; Me: methysergide; Ke: ketanserin; SB-26: SB-269970; SB-20: SB-204070; Ro: Ro 04-6790; I: increase; D: decrease; N: no change; +: effective in blocking the effect of 5-HT; −: ineffective in blocking the effect of 5-HT.…”
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Additional Analysis of visually induced calcium transients in Fig 6.
Published 2020“…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …”
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Schematic representation of possible intracellular 5-HT signaling pathways in chondrocytes.
Published 2017“…Then, the phosphorylated ERK1/2 level is increased through both activation of PKCε and PKCζ; as a result, CCN2 production is decreased. Furthermore, independent of PKC, 5-HT may transmit a certain unknown signal to JNK, which also inhibits the CCN2 production in chondrocytes.…”