Genomic inactivation of the <i>PIWI</i> gene in <i>L. infantum</i> and <i>L. major</i> strains leads to a decrease in amastigote growth and disease pathology. by Prasad K. Padmanabhan (85254)

Preliminary experiment. by Takahiro Tanaka (159434)

“…However, grip strength gradually declined from 6 weeks, and showed a significant difference at 7 weeks after surgery (P < 0.0001: two-way ANOVA) After that, the strength continued to decrease gradually, reaching approximately 10.5 N at 26 weeks postoperatively.…”

Image_2_Reaching and maintaining higher dietary diversity is associated with decreased risk of all-cause mortality: A longitudinal study from the China Health and Nutrition Survey.... by Xiaochen Qu (13861271)

“…In summary, reaching and maintaining a higher DDS was associated with a decreased risk of all-cause mortality. …”

Image_1_Reaching and maintaining higher dietary diversity is associated with decreased risk of all-cause mortality: A longitudinal study from the China Health and Nutrition Survey.... by Xiaochen Qu (13861271)

“…In summary, reaching and maintaining a higher DDS was associated with a decreased risk of all-cause mortality. …”

Jump into a New Fold—A Homology Based Model for the ABCG2/BCRP Multidrug Transporter by Laura László (3221631)

“…The recently published high resolution structure of a close homologue, the ABCG5-ABCG8 heterodimer, revealed a new ABC transporter fold, unique for ABCG proteins. …”

Image_1_Reduced Ca2+ transient amplitudes may signify increased or decreased depolarization depending on the neuromodulatory signaling pathway.PDF by Arunima Debnath (13136676)

“…However, OA antagonizes 5-HT modulation of 1-oct avoidance behavior, suggesting that OA may signal through a different pathway. …”

ROS levels, cell viability, and LDH and Fe²⁺ content in HT22 cells after XMU-MP-1 treatment. by Lu Li (14069)

Impaired Ubr5 function results in increased canonical and decreased non-canonical HH signalling. by David Mellis (2833469)

Optimal MUAC cut-off points by gender in different age categories for screening individuals with underweight, overweight and obesity. by Sheikh Arafat Rahman (21799685)

Most miRNAs in Ago1 RISC are stable with age whereas transposon siRNAs in Ago2 RISC decrease with age. by Siobhan Gartland (14129274)

“…(B) miRNAs in Ago1 RISC from old and young females are plotted as percentage of mapped reads. miR-34-5p and miR-14-3p do not change by 2-fold. miR-318-3p and miR-994-5p decrease by 2-fold with age. …”

GXM decreases the trans-endothelial electrical resistance (TEER) and transmigration of <i>C</i>. <i>neoformans</i> through HBECs in a blood brain barrier (BBB) model. by Hiu Ham Lee (15374677)

Aldolase A critically regulates the assembly of v-ATPase and phagosome acidification. by Saray Gutiérrez (11473528)

Depletion of PfPKAc in NF54/AP2-G-mScarlet/PKAc cKD parasites leads to a block in merozoite invasion and decreases gametocyte rigidity. by Eva Hitz (10877688)

Higher concentrations of HDACi LBH589 further increase PR and decrease Myc expression in endometrial cancer cells. by Tamar Kavlashvili (849072)

Validation of a New Scoring Scale for Behavioral Assessment of L‑Dopa-Induced Dyskinesia in the Rat: A New Tool for Early Decision-Making in Drug Development by Simon Loiodice (4715610)

“…The rating scale was sensitive enough to highlight a dose-dependent amantadine-mediated decrease (about 2.2-fold) in LID score. …”

Measured glucose concentration at time points 1, 5, 10 min, and 4h in 100 <i>μ</i>L incubations. by Hamidreza Arjmandi (19657263)

SARS-CoV-2 inhibition by MAP30 and Momordin. by Norman R. Watts (1964959)

γHV-68 EAE mice show increased levels of pro-inflammatory cytokines and chemokines and a decreased anti-MOG IgG1/IgG2a ratio in the serum. by Costanza Casiraghi (164176)

European Credit Transfer System grades (ECTS) (A) and highest educational level (B) according to test scores. by Anders H. Hjulmand (18476019)

Image_5_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”