PV1-treated mice exhibited a decrease in overall activation of T lymphocytes. by Pedro Henrique Papotto (791904)

Coibamide A induces a time- and concentration-dependent decrease in plasma membrane integrity. by Andrew M. Hau (418935)

Gene expression of 5-HT transporter (5-HTT), 5-HT_1A receptor (5-HT_1AR) and tryptophan hydroxylase-2 (TPH2) in the raphe. by Thibault Renoir (348572)

“…<p>Measuring mRNA levels of several genes encoding proteins that regulate 5-HT homeostasis, we found significant genotype-sex interactions for both mRNA levels of (A) 5-HTT and (B) TPH2 but not for (C) 5-HT_1AR gene expression. …”

Sildenafil decreases intestinal transit time in a DSS-recovery model of IBS. by Sarah K. Sharman (3966476)

Number of pulmonary endothelial cells decreased upon infection and started to proliferate during resolution to restore their number by 15 dpi accompanied by decreased endothelial a... by Emilie Pollenus (10147748)

<i>Ep300</i> siRNA suppressed osteoblast differentiation and decreased histone lactylation levels. by Erika Minami (17583343)

Expression of 5-HT_4(b), 5-HT_2A, 5-HT_2B and 5-HTT mRNA in left ventricular myocardium. by Trond Brattelid (290970)

“…(A) 5-HT_4(b) mRNA levels decreased with foetal and neonatal development and the level in adult myocardium was one tenth of that at day -3 but reappeared in HF; (B) 5-HT_2A mRNA expression increased at birth (day 1), decreased during neonatal development and was unaltered in HF; (C) 5-HT_2B mRNA expression was transiently increased at birth (day 1) compared to adult (day 113) and not changed in HF; (D) 5-HTT mRNA expression was lower in foetal hearts compared to neonatal, adult, Sham and HF which all showed a similar expression level. …”

Ageing results in an abrupt decrease in overall neurogenesis in the mouse DG. by Joana Gil-Mohapel (462002)

“…(C) An estimation of overall neurogenesis based on the total number of BrdU-positive cells that survived the 42-day period multiplied by the proportion of BrdU-positive cells that acquired a mature neuronal phenotype indicates an age-induced significant and abrupt decrease in the overall number of new neurons. *** <i>p</i> < 0.001 between 1.5 and 3 months and between 3 and 6 months. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

2-ME decreases blood pressure in Sprague Dawley rats. by Weiyu Chen (2216251)

Probucol prevents 3-NP-induced decreases in body weight. by Dirleise Colle (422124)

Acute JMV2959 treatment decreases alcohol preference in rats. by Petra Suchankova (400313)

“…<p>(A) Acute administration of the GHS-R1A antagonist JMV2959 (1 or 3 mg/kg) decreases the alcohol preference compared to vehicle at 1 hour time interval in rats voluntarily consuming alcohol for two and five months before the treatment. …”

Acute JMV2959 treatment decreases alcohol intake in rats. by Petra Suchankova (400313)

“…<p>(A) The acute effects of the GHS-R1A antagonist JMV2959 (1 or 3 mg/kg) administration on alcohol intake was evaluated at 1 hour time interval after both two and five months of voluntary alcohol consumption. …”

Ru-NO plus propolis decreased protein nitration at the lesion site. by Milena Menegazzo Miranda (739250)

Damage accumulation decreases elongation rates and displaces growth equilibrium. by Audrey Menegaz Proenca (845486)

“…<p>All panels depict MG1655 wild-type <i>E</i>. <i>coli</i>. (A) Exposure to phototoxic damage led to decreasing elongation rates in all treatment levels (length of exposure, every 2 min: 70 ms, 700 ms, 1 s, 1.5 s, 3 s). …”

Anandamide decreases locomotor activity and rearing in small open field. by Adriaan W. Bruijnzeel (2605954)

Adoptive transfer of mature NK cells decreases the incidence of BA and improves survival, and the level of VP4 in cholangiocytes and the incidence of BA are decreased as the age of... by Yinrong Qiu (345978)

PRV-induced infertility is caused by decreased P4 level. by Bing-Qian Su (8616981)

JBPOS0101 decreased Amyloid Beta (Aβ) aggregates in the cortex and hippocampal regions in 5xFAD mouse brains. by Jihoon Jeong (4852690)