Decreased transcription of <i>prs</i> results in decreased growth. by Javiera Norambuena (137228)

Systemic role of the peripheral 5HT. by Igor Erjavec (2265613)

“…Elevated 5HT bidirectionally influences the plasma insulin level (green-red arrow) and induces the hyperthrophy of pancreatic β-cells (dashed arrow), leading to type 2 diabetes with an increased plasma glucose, insulin resistance, glucose intolerance, visceral fat volume and decreased muscle strength. …”

Occupancy estimation. by Yukiko Hori (299784)

Subjects:

Prenatal treatment decreases proliferation and increases apoptosis in small intestine. by Fátima Ramalhosa (3095712)

“…(B) Proliferation rate is decreased within the crypts in <i>iuGC</i> rats, n = 3, 4, 5 CTR and n = 3, 6, 3 <i>iuGC</i>. …”

<i>Gng5^−/−</i> mutants have decreased cell proliferation and survival. by Anne M. Moon (134982)

Genotype frequencies of the polymorphisms <i>rs1799971</i> (OPRM1), <i>rs6296</i> (5-HT_1A) and the triallelic 5-HTT for the whole group, as well as fibromyalgia (FM) pat... by Jeanette Tour (10790855)

Respiratory network responses to systemic 5-HT_2AR and 5-HT_2BR activation. by Marcus Niebert (183419)

“…Statistical analysis (paired t-test) is denoted in the panels on the right side. (<b>A</b>–<b>C</b>) Action of 5-HT_2AR and 5-HT_2BR ligands in the perfused brainstem preparation. …”

Decrease in PP2A activity increases phosphorylation of p38MAPK, pMAPKAPK2 and Hsp27 in CD133+ cells. by Shih-Pei Lin (117914)

Decrease in vRNA in brain during antiretroviral therapy. by Sonny R. Elizaldi (9684796)

MK-STYX decreases RhoA activation. by Brittany M. Flowers (670483)

“…<p>(<b>A</b>) PC12 cells were transfected with pMT2 or pMT2-FLAG-MK-STYX-FLAG. 24 hr post-transfection cells were stimulated with 100 ng/ml NGF, and lysed at the indicated time points. …”

M2 macrophages decrease alkaline phosphatase activity through Wnt signalling pathways. by Jesús Cosín-Roger (123861)

NR4A1 expression does not decrease after inhibition of p38, JNK and Src pathways. by Glenda Eger (636934)

Effect of 2%, 4%, and 6% HQ cream on hippocampal 5-HT level and 5-HT_{1A /1B} receptor expression. by Huali Wu (349567)

“…<p>(A) HQ decreases hippocampus 5-HT level in a dose-dependent manner. …”

Additional Analysis of visually induced calcium transients in Fig 5. by Maureen M. Sampson (9322886)

“…<p>Visually induced calcium transients were recorded in flies expressing L2-split-GAL4>GCaMP6f as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g005" target="_blank">Fig 5</a>. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

NgR1 KO mice exhibited an increase in excitatory synapses and a decrease in inhibitory synapses, indicating an imbalance of synaptic transmission. by Jinwei Zhang (462455)

“…The inhibitory synaptic density of NgR1 mice showed a significant decrease when compared to WT mice (***P <  0.001). …”

Normalized pressure pain thresholds (PPTs) (mean ± SEM) at start, middle, end and 5 minutes after a standardized tourniquet test. by Jeanette Tour (10790855)

NG2 knockdown in GBM xenografts increased vascular reabsorption, decreased plasma volume and normalized tumour vasculature. by Jian Wang (5901)

Matrix crosslinking decreases cell migration persistence. by Michael Pamonag (12295175)