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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
ht decrease » _ decrease (Expand Search), we decrease (Expand Search), step decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
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Design, Synthesis, and Biological Evaluation of New Peripheral 5HT<sub>2A</sub> Antagonists for Nonalcoholic Fatty Liver Disease
Published 2020“…Here, structural modifications of pimavanserin (CNS drug), a 5HT<sub>2A</sub> antagonist approved for Parkinson’s disease, led us to synthesize new peripherally acting 5HT<sub>2A</sub> antagonists. …”
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Impact of 5HT stimulation on the plasma membrane density of truncated and mutant transporters.
Published 2009“…<p>CHO cells expressing truncated or mutant forms of transporter were either directly <i>(A and B)</i> or after stimulated with 100 μM 5HT <i>(C and D)</i> subjected to the cell surface biotinylation assays. …”
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Flibanserin’s neuroprotective effects are 5-HT<sub>1A</sub> receptor-mediated.
Published 2016“…A 6 mg/kg dose of flibanserin in 5-HT<sub>1A</sub> knockout mice (5-HT1A KO + 6 mg/kg Flibanserin, <i>red</i>) resulted in average receptor plus thickness that was not significantly different from vehicle-injected and naïve mice. …”
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Data_Sheet_1_hsa-miR-3177-5p and hsa-miR-3178 Inhibit 5-HT1A Expression by Binding the 3′-UTR Region in vitro.doc
Published 2019“…Dual luciferase reporter assay and Western Blot were used to confirm the effect of miRNA mimics and inhibitors on endogenous 5-HT1A receptors. In all cell lines, gene expression of the −17 bp to +443 bp fragment containing the complete sequence of the 3′-UTR region was significantly decreased, although mRNA quantification was not different. …”
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Human 5-HT<sub>4</sub>-based RASSLs.
Published 2007“…<p>A signal peptide and the FLAG epitope were added to the N-terminus of the human 5-HT<sub>4</sub> receptor. …”
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117
5-HT<sub>7</sub>Dro knock-down decreases frequency of courtship behaviors.
Published 2011“…When compared with the parental lines 5-HT<sub>7</sub>-Gal4 (Gal4) and UAS-sym-5-HT<sub>7</sub>-dsRNA (UAS), the frequency of licking, curling and copulation attempts was significantly decreased. …”
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Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T...
Published 2022“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC<sub>(tofacitinib, 0–∞)</sub> and a 9.61-fold increase of colonic AUC<sub>(tofacitinib, 0–12h)</sub>, compared with tofacitinib at a molar equivalent oral dose. …”
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