Image_4_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_2_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_1_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image5_The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice.JPEG by Vladimir M. Pogorelov (133492)

“…Despite these benefits, the hallucinogenic actions of these drugs at the serotonin 2A receptor (5-HT2AR) limit their clinical use in diverse settings. …”

U87MG glioma cells transduced with gal-3 shRNA demonstrate decreased tumor size and growth. by Rafael Yamashita Ikemori (698128)

“…The inoculation of U87MG gal-3 shRNA cells in the flank of nuce mice (n = 5) demonstrated a decrease in tumor size and growth compared to the U87MG scramble shRNA (n = 6). …”

The 5’SS motif decreases mRNA stability and promotes nuclear retention. by Eliza S. Lee (715538)

“…Note that the relative level of <i>c-ftz-Δi-V5-His</i> decreases over the first 60 min until 40–50% of the mRNA remains, after which point the ratio is stable. …”

The mitochondrial ROS-counteracting protein PRDX3 is decreased in NRF2i-DMA cells. by Bo-hyun Choi (630240)

Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons. by Sara Hijazi (21656615)

“…The number of branch points in PV interneuron axons from cuprizone-treated mice was significantly decreased compared to control mice (<i>t test; n = 10/9 cells per group, *p < 0.05</i>). …”

Homozygous deletion of <i>ERG251</i> leads to the decreased ergosterol accumulation in the absence of FLC and decreased production of toxic dienol in the presence of FLC. by Xin Zhou (54275)

Ludmila Belayev 12-point scoring between groups. by Guangxiao Ni (19713106)

Subjects:

Ablation of Tph1 gene in dams decreased circulating serotonin and calcium on day 1 and 10 of lactation. by Jimena Laporta (383836)

Hormone therapy decreased β-amyloid load and improved cognitive performance in early middle-aged mice. by Amy Christensen (4062937)

Structurally distinct inhibitors of Chk1 decrease Chk1 nuclear fluorescence following heating in a low well volume. by Andrew J. Massey (239469)

Replacing i3 of Rs1 with that of 5-HT_1A results in a receptor, Rs1-i3-5-HT_1A, with weak G_isignaling. by Wei Chun Chang (43479)

“…<p>(A) Rs1-i3-5-HT_1A chimera decreased cAMP accumulation. …”

<i>patDp</i>/+ mice have decreased tissue 5-HT and increased tissue DA levels during postnatal development. by Kota Tamada (235174)

Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV by Henryk Majczyński (830716)

“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT₂ (Cyproheptadine; Cypr), 5-HT_2A neutral antagonist (Volinanserin; Volin), 5-HT_2C neutral antagonist (SB 242084), and 5-HT_2B/2C inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”

Stat1 activation is strongly decreased by MNV-S99 infection. by Sandra Niendorf (2832785)

Panc1 cells were transfected with siHOTTIP, siHOTAIR or siMALAT-1, and changes in gene expression were determined using human HT-12 V4 expression bead chip arrays. by Yating Cheng (523668)

Upregulation of 5-Hydroxytryptamine Receptor Signaling in Coronary Arteries after Organ Culture by Chun-Yu Deng (293972)

“…<div><p>Background</p><p>5-Hydroxytryptamine (5-HT) is a powerful constrictor of coronary arteries and is considered to be involved in the pathophysiological mechanisms of coronary-artery spasm. …”

5-HT₇Dro modulates courtship and mating. by Jaime Becnel (218896)