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421
All data points from Fig 9.
Published 2025“…Following a remyelination period of 5 weeks, PV interneuron properties were only partially recovered, suggesting that transient juvenile demyelination leads to long-lasting impairments of PV interneuron function. …”
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422
All data points from Fig 7.
Published 2025“…Following a remyelination period of 5 weeks, PV interneuron properties were only partially recovered, suggesting that transient juvenile demyelination leads to long-lasting impairments of PV interneuron function. …”
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423
All data points from Fig 6.
Published 2025“…Following a remyelination period of 5 weeks, PV interneuron properties were only partially recovered, suggesting that transient juvenile demyelination leads to long-lasting impairments of PV interneuron function. …”
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424
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425
Production of O<sub>2</sub><sup>ꜙ</sup>, NO and cyclic GMP by 5-HT.
Published 2009“…<p>A, O<sub>2</sub><sup>░</sup> production was measured by EPR spectrometry in the absence or in the presence of 5-HT 100 µM (black column and white column respectively). …”
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426
Rate-limiting enzymes tyrosine hydroxylase (catecholamines) and tryptophan hydroxylase (5-HT) post-stress.
Published 2014“…<p>Tyrosine hydroxylase elevation in the PFC (A) and hippocampus (B) substantiated the findings of elevated levels of NE and DA, while down-regulated tryptophan hydroxylase in the PFC (C) and hippocampus (D) confirmed decreased levels of 5-HT. …”
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427
5-HT-induced cardiomyocyte injury required the presence GC or NE <i>in vitro</i>.
Published 2014“…<b>A.</b> The cell viability of cardiomyocytes treated with 10<sup>−8</sup> M 5-HT and 10<sup>−6</sup> M GC decreased significantly compared with the control. …”
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428
5-HT<sub>7</sub>Dro knock-down results are consistent with pharmacological studies.
Published 2011“…C) The activity of male flies carrying either the 5-HT<sub>7</sub>Dro-GAL4 element (GAL4, white bar), the UAS-sym-p5-HT<sub>7</sub>RNAi element (UAS-RNAi, black bar), or both (F1, gray bar) was measured using the DAMS system for five days. …”
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429
Tunicamycin produces a concentration- and time-dependent decrease in cell viability in SH-SY5Y cells concomitant with caspase-3 activation.
Published 2013“…<p>(A) Treatment of SH-SY5Y cells with tunicamycin (0.1–5µM) for 24 h caused a progressive decrease in cell viability as measured by Calcein AM cleavage assay. …”
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430
(R)-albuterol decreases cytokine mRNA levels in activated T cells
Published 2011“…</p><p></p> (R)-albuterol, (S)-albuterol or racemic albuterol (R + S) at a dose (10M) were added to T (EL-4) cells pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP). …”
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431
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432
Psychological stress in aged female mice causes acute hypophagia independent of central serotonin 2C receptor activation
Published 2017“…The administration of a serotonin 2C receptor (5-HT<sub>2C</sub>R) antagonist suppressed plasma corticosterone but did not affect the reduction in food intake. …”
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433
Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study
Published 2020“…In total, 291 of 714 individuals experienced 762 hospitalised AECOPD during five-year follow up. Poorer performance of SPPB was associated with both higher rate (IRR 1.08 per 1 point decrease, 95% CI 1.01 to 1.14) and increased length of stay (IRR 1.18 per 1 point decrease, 95% CI 1.10 to 1.27) for hospitalised AECOPD. …”
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434
Flow chart of the study procedures.
Published 2023“…</p><p>Conclusions</p><p>In a mostly HIV patient population, RPR titer can show more than four-fold spontaneous increase or decrease within 1–3 months. …”
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435
Mice carrying 100P mutations show region-specific decreases in proportions of PV-expressing cells.
Published 2016“…<p>(<b>A</b>) Significant decreases in the proportions of PV+ cells were observed in fSSp, SSp, vAud and in Vis, but not MPFC. …”
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436
5-HT2A and Foxo are required in R2/R4 neurons to mediate the effects of death perception on lifespan.
Published 2023“…<p>Knock-down of <i>5-HT2A</i> mRNA expression in R2 alone (A), in R4d alone (B), or in R2/R4 inhibited lifespan differences due to death perception. …”
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437
Glial 5-HT<sub>2a</sub> receptors are necessary and rate limiting for experience-dependent synaptic glomeruli pruning.
Published 2024“…The Or42a OSN innervation volume with glial <i>5-HT</i><sub><i>2A</i></sub><i>R</i> OE is very significantly decreased in comparison to the control EB condition (<i>p</i> = 4.64 × 10<sup>−10</sup>). …”
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438
Developmental change in 5-HT<sub>1A</sub> binding in known cause of death controls (predischarge and postdischarge combined).
Published 2025“…Binding in these nuclei are visually (top row) and quantitatively (bottom row) decreasing with PC age, the latter shown with plots of 5-HT<sub>1A</sub> binding vs PC age. …”
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439
Stress responses after knockdown of octopamine receptor OAMB and serotonin receptor 5-HT<sub>1A</sub> in IPCs.
Published 2014“…In an earlier study it was shown that 5-HT<sub>1A</sub> knockdown decreased starvation resistance <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0099732#pone.0099732-Luo1" target="_blank">[22]</a>. …”
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440
Table_1_Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT1A-Mediated cAMP Signaling.DOCX
Published 2020“…Background<p>Major depressive disorder (MDD) is a severe mental disorder related to the deficiency of monoamine neurotransmitters, particularly to abnormalities of 5-HT (5-hydroxytryptamine, serotonin) and its receptors. …”