The content of pyridine nucleotides in FVB and Mb hearts. by Jianxun Wang (290485)

“…(E) A significant decrease of NADPH content was observed in FVB and Mb hearts after TAC. …”

Cellular activity of (T,C)-containing TFO/LNAs: inhibition of transcription elongation by Erika Brunet (27183)

“…Acr-16TC/po = Acr-16TC/po, 3′-modified by incorporation of a propylamine group. () Ratio of (Firefly/) RNA levels was deduced from competitive RT–PCR (Materials and Methods): decrease of RNA level was compared with that obtained for transfection of (+)PPT/luc and RL-TK plasmids in absence of TFO/LNAs.…”

Image1_Inflammation aggravated the hepatotoxicity of triptolide by oxidative stress, lipid metabolism disorder, autophagy, and apoptosis in zebrafish.TIF by Chenqinyao Li (13521178)

“…Compared with the Triptolide group, LPS-Triptolide cotreatment exacerbate the liver injury with a remarkable decrease of liver size and liver-specific fluorescence intensity, accompanied by significant elevation of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities. …”

Nanocurcumin Prevents Hypoxia Induced Stress in Primary Human Ventricular Cardiomyocytes by Maintaining Mitochondrial Homeostasis by Sarita Nehra (800457)

“…Nanocurcumin prevented translocation of p53 to mitochondria by stabilizing mitochondrial membrane potential and de-stressed hypertrophied HVCM cells by significant restoration in lactate, acetyl-coenzyme A, pyruvate and glucose content along with lactate dehydrogenase (LDH) and 5' adenosine monophosphate-activated protein kinase (AMPKα) activity. …”

Image 1_Global burden of tuberculosis attributable to diet low in whole grains from 1990 to 2021, with projection to 2045.pdf by Xiaoning Lu (206322)

“…</p>Results<p>In 2021, TB-DLWG accounted for 177,303.55 DALYs globally, representing an 8% decrease from 1990. The number of deaths was 5,539.13, a 12% reduction. …”

Construction and Performance Evaluation of Functional Coating with Multi-Layered Structure on the Surface of Cashmere Fibers Based on Dispersed Graphene by Cationic Waterborne Poly... by Heng Quan (588349)

“…The results show that the cashmere textile obtained 1.0% (o.m.f. on mass of fabric) weight gain rate (WGR) under the foam bottom coating process, correspondingly, obtained 3–4% (o.m.f.) weight gain rate (WGR) under traditional dipping process, the pilling resistance grade of cashmere textile is improved to Grade 4–5 from Grade 1–2. The semi-embed state of graphene in the “surface coating” resin film on cashmere surface results in the decrease of static voltage half-life from 180 s to about 2 s. …”

Efficacy of electrical Russian current stimulation after end-to-side neurorrhaphy of the common fibular nerve: electroneuromyography and muscle strength analysis by Mariana Moreno Gabira (7396454)

“…The Russian Current was started 5 days after neurorrhaphy and applied to the cranial tibial muscle of the ENRSG, 3 times a week, totaling 36 sessions. …”

Heterobimetallic Samarium(III) and Titanium(IV) Complexes with Bifunctional Catalytic Properties by Fengying Zhou (289435)

“…Reaction of the bis-ligand-chelated samarium complex [Sm(Hbptd)(H₂bptd)] (<b>1</b>; H₃bptd =1,9-bis(2-pyrrolyl)-2,5,8-triazanona-1,8-diene), in which a pyrrolyl ring is dangling and metal-free, with Ti(NMe₂)₄ yielded the heterometallic complex [Sm(Hbptd)(THF)(bptd)Ti(NMe₂)₂] (<b>2</b>). …”

Simplified Insulin-like growth factor 1 receptor (IGF1R) and mTORC1 and mTORC2 signaling in relation with EWS-FLI1. by Vivek Subbiah (353745)

“…Now mTORC1 complex (mTOR + mLST8+Raptor) is activated by GTP-bound Rheb and phosphorylates proteins like S6K. This starts a negative feedback loop to modulate auto-activity, through S6K-mediated pathway decrease in the activation of PI3K. …”

CHD8 depletion by RNAi is detrimental to B-ALL cells <i>in vitro</i> and <i>in vivo</i>. by Jennifer R. Shingleton (829013)

“…An increase in the percentage of GFP+ cells indicates positive selection conferred by shRNA expression, while a decrease indicates negative selection. <b>(B)</b> Western blot showing decreased CHD8 expression in B-ALL cells conferred by both shRNAs (4 days following retroviral infection). …”

Dietary lysine requirement of adult lambari ( Astyanax altiparanae ) (Garutti and Britski, 2000) by Daniel Abreu Vasconcelos Campelo (5839391)

“…Fish fed 12.13 to 19.92 g kg−1 lysine showed increased weight gain and percent weight gain, and fish from those treatments also showed improvement in final carcass quality by a decrease in whole-body lipid content. Fish fed 12.13 g kg−1 lysine showed lower ALT and AST activities in blood serum when compared with fish fed the highest lysine levels. …”

Data_Sheet_1_Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice.PDF by Cheng-Feng He (12540442)

“…We found that diabetes enhanced the MCAO-induced elevation of NRSF in the hippocampus in accompany with an elevation of its corepressors, HDAC1, and mSin3A, and decrease of β-TrCP. By using histological/immunofluorescence staining and neurobehavioral testing, our results showed that the brain damage and learning/memory impairment were aggravated in diabetic ischemic mice but significantly attenuated after stereotaxic injection of NRSF-shRNA. …”

Cytotoxicity, and antimicrobial and physicochemical properties of sealers incorporated with Uncaria tomentosa by Nathália Lima CALDAS (12656245)

“…The incorporation of UT was associated with a decrease in flow, for both sealers, an increase in AH Plus setting time, increase in MTA Fillapex pH values, and solubility (after 14 days), for both sealers (p < 0.05). …”

Reduction of organelle motility by removal of potassium and other solutes by John W. Murray (2841077)

“…However, extracellular flux analysis showed near normal mitochondrial oxygen consumption and only a small decrease in extracellular acidification, the latter suggesting decreased glycolysis or proton efflux. …”

Image_2_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.tif by Fiona S. McDonnell (17106334)

“…Introduction<p>Extracellular matrix (ECM) materials accumulate in the trabecular meshwork (TM) tissue of patients with glaucoma, which is associated with a decrease in aqueous humor outflow and therefore an increase in intraocular pressure. …”

Evaluation of the physical, chemical and mechanical properties of starch/PVA/bentonite clay films modified with glycidyl methacrylate by Alberto Gonçalves Vieira de Carvalho Neto (10472190)

“…This strategy also resulted in a 25% improvement in tensile strength, maintaining the same Young’s modulus and slight decrease in thermal stability (onset of degradation 14 ° C lower). …”

Table 1_Antimicrobial susceptibility profiles of commensal Clostridium perfringens isolates from chickens in Hungarian poultry farms between 2022 and 2023.docx by Ádám Kerek (14263613)

“…</p>Results<p>Our findings revealed a decrease in the efficacy of penicillin-based antibiotics, which are primary choices for treating C. perfringens-related infections, with resistance observed in 48.3% of isolates for penicillin and 20.7% for amoxicillin. …”

Effect of point mutations on the kinase activity of c-Abl. by Nicole Dölker (641799)

“…The kinase activity was normalized to the amount of protein and to the activity of the wild-type CD or SH2-CD construct. <b>A</b> M297L was found to decrease kinase activity, whereas M297G had an activating effect in the absence of the SH2 domain. …”

3BrP effect on glycolytic enzymes as well as on differentiation markers assessed via embryoid body (EB) formation. by Ana Sofia Rodrigues (491559)

“…Results were normalized to beta-Actin protein levels and are represented as percentage relative to the control; the results represent n = 4. Right: a representative blot demonstrating the decrease in protein levels for glycolytic enzymes. …”

Polyheteroaryl Oxazole/Pyridine-Based Compounds Selected in Vitro as G‑Quadruplex Ligands Inhibit Rock Kinase and Exhibit Antiproliferative Activity by Daniela Verga (2202436)

“…Herein, we report on the synthesis of parent compounds bearing either amino side chains (TOxaPy-1–5) or featuring an isomeric oxazole-pyridine central connectivity (iso-TOxapy, iso-TOxapy 1–3) or a bipyridine core (iso-TOxabiPy). …”