Chloroquine (CQ) treatment blocks autophagosome–lysosome fusion and induces myopathy in the larva. by Jonathan Zirin (483506)

“…(M) Quantification of autophagy changes due to <i>Atg</i> gene knockdown in <i>Dmef2</i>–<i>Gal4</i>, <i>UAS</i>–<i>GFP</i>–<i>Atg8</i> larvae starved on low-nutrient food +2.5 mg/ml CQ for 6 h. Each of the 10 <i>UAS</i>–<i>Atg</i> RNAi transgenes tested caused a highly significant decrease (<i>p</i><.01) in the total area of GFP–Atg8 vesicles. …”

Individual recording analysis. by Sonya Marshall-Gradisnik (3525122)

“…PregS amplitude = (B)–(A) and Ononetin amplitude = (C)–(D). PregS was effective when presented with an increase at +100 mV current and Ononetin was effective when there is a decrease at +100 mV current. …”

Amastigote susceptibility results of the <i>in vivo</i> resistance selection procedure to PMM-MIL combination therapy. by Sarah Hendrickx (321143)

“…Exposure to PMM alone (ITMAP263 PMM) revealed a significant susceptibility decrease (indicated in bold)[<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0005620#pntd.0005620.ref014" target="_blank">14</a>]. …”

Numerical analysis of the effective stiffness of elastomeric bearing pads under precast beams for the limit load of lateral instability by L. C. REIS (8652054)

Do sit-to-stand performance changes during gait acquisition? by Alana Maria Ferreira Guimarães Bastos (12838317)

“…At the gait acquisition period we found a significant decrease in the final trunk flexion angle and an increase in amplitude of the trunk flexion. …”

Table 1_Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy.docx by Shuai Sun (775057)

“…The time invested in the oART workflow was recorded at each step. Acute toxicities were classified following the Common Terminology Criteria for Adverse Events (CTCAE) version 5.0.…”

Heme dissociation kinetics for wild-type and mutant IsdX1. by MarCia T. Ekworomadu (178999)

“…Proteins were re-constituted with heme, excess heme removed by gel filtration chromatography, and holo proteins (1 µM) mixed with H64Y/V68F apo-Mb (26 µM) at 25°C in PBS, pH 7.4. Time courses for hemin dissociation the IsdX1 variants were determined by measuring the difference between in the increase in absorbance at 419 nm (peak for holo H64Y/V68F holo-Mb) and the decrease in absorbance at 380 nm (strong absorbance by holo-IsdX1).…”

QTL mapping of male sterility and transmission pattern in progeny of Satsuma mandarin by Shingo Goto (739660)

“…The QTL for APF (<i>MS-F1</i>) was detected on linkage group 6 with a significant LOD score (5.71) and 63.6% of variance explained. …”

Table_1_Impacts of glacial and sea-ice meltwater, primary production, and ocean CO2 uptake on ocean acidification state of waters by the 79 North Glacier and northeast Greenland sh... by Agneta Fransson (471604)

“…This was most pronounced near the 79NG front in 2012, where surface stratification was most pronounced coinciding with large glacial meltwater fractions. Freshening decreased Ω_Ar by 0.4 at the 79NG front was compensated by biological CO₂ drawdown by ~0.5. …”

Regulation of GGA expression alters APP processing and sAPP secretion. by Bjoern von Einem (751380)

“…Additionally, deletion of GGA2-VHS led to an even stronger decrease in sAPP levels. Experiments were carried out in triplicate; shown are the results of n = 5 independent experiments. …”

Features of assembled parent communities. by Pablo Lechón-Alonso (11663433)

“…<b>B</b>: Change in proportion of species m-preferences consumers before and after assembly (Δ<i>m</i>_<i>r</i>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009584#pcbi.1009584.e017" target="_blank">Eq 5</a>, y axis) as a function of the number of metabolic preferences (x axis), for three different values of <i>k</i>_<i>c</i> (legend in panel C), calculated after each simulation, and averaged across simulations. …”

Effect of Flow Conditions on the Dynamics of Chemical Demulsification in Highly Viscous Emulsion Flow by Samuel Vitor Saraiva (17984521)

High dose wIFN-α significantly induced intrahepatic expression of T cell, NK cell and IFN-γ response genes. by Simon P. Fletcher (793613)

“…</p><p>^aFold-change ratio values relative to time-matched placebo animals (n = 5–12) are displayed, with underlining denoting statistical significance (FDR<0.05). …”

Supplementary Material for: Impact of Medium Cut-Off Dialyzers on Patient-Reported Outcomes: COREXH Registry by Alarcon J.C. (9627059)

“…No significant differences in the number of symptoms (DSI, <i>p =</i> 0.1) were observed, although their severity decreased (<i>p</i> = 0.009). <b><i>Conclusions:</i></b> In conventional HD patients, the expanded clearance of large middle molecules with MCO-HD membranes was associated with higher health-related quality of life scores and a decrease in the prevalence of RLS.…”

Table_1_The Influence of Social Isolation on Social Orientation, Sociability, Social Novelty Preference, and Hippocampal Parvalbumin-Expressing Interneurons in Peripubertal Rats –... by Milica Potrebić (12494344)

“…The main findings are the following: (1) in GH rats, the preference for social space is not evident regardless of animals’ age, while sociability becomes apparent in mid-adolescence strictly through consummatory behavior, along with complete SNP (appetitive, consummatory); (2) SH promotes staying in a social chamber/space regardless of animals’ age and produces an appetitive preference for it only in early-adolescent animals; (3) SH promotes sociability (appetitive, consummatory) regardless of the animals’ age and prevents the SNP; (4) the preference for a social odor is displayed in all the groups through consummatory behavior, while appetitive behavior is evident only in SH rats; (5) the response to social odors does not commensurate directly to the response to conspecifics; (6) SH does not influence PVI in the hippocampus, except in the case of early-adolescence when a transient decrease in the dentate gyrus is observed. …”

Image_1_Impacts of glacial and sea-ice meltwater, primary production, and ocean CO2 uptake on ocean acidification state of waters by the 79 North Glacier and northeast Greenland sh... by Agneta Fransson (471604)

“…This was most pronounced near the 79NG front in 2012, where surface stratification was most pronounced coinciding with large glacial meltwater fractions. Freshening decreased Ω_Ar by 0.4 at the 79NG front was compensated by biological CO₂ drawdown by ~0.5. …”

Table_1_Fronto-parietal theta high-definition transcranial alternating current stimulation may modulate working memory under postural control conditions in young healthy adults.doc... by Yanwen Xiao (16972179)

“…</p>Results<p>Within the tACS group, we found a 5.3% significant decrease in working memory response time under the dual-task following tACS (t = −3.157, p = 0.005, Cohen’s d = 0.742); phase synchronization analysis revealed a significant increase in the phase locking value (PLV) of θ band between F3 and P3 after tACS (p = 0.010, Cohen’s d = 0.637). …”

Table_1_How Free-Viewing Eye Movements Can Be Used to Detect the Presence of Visual Field Defects in Glaucoma Patients.docx by Birte Gestefeld (11589424)

“…On average, glaucoma patients had a significantly lower VP than the controls, with this decrease depending on the specific video viewed.…”

Transparent Sodium Lignosulfonate/Phosphorylated Sodium Alginate/Cellulose Composite Films with Flame-Retardant and UV to Blue Light-Shielding Performance by Jingyuan Zhang (6535169)

Image_3_Real clinical experience after one year of treatment with tolvaptan in patients with autosomal dominant polycystic kidney disease.JPEG by Javier Naranjo (13879235)

“…The main causes of treatment withdrawal were the aquaretic effects (11%), eGFR deterioration (5%), and hepatic toxicity (2.3%). eGFR decreased significantly after 1 month of treatment without further changes. …”