Change in levels of 5HT and its related substances in the brain of queen associated with early colony establishment. by Hitoshi Aonuma (50438)

“…B: Change in level of 5HT in the brain of queen associated with early colony establishment. 5HT significantly decreased after queen started establishing a colony. …”

Wnt signaling decreases the recruitment of RAB8a to basal bodies. by Cheng Yuan (160315)

Removal of the A-B linker did not decrease PIP₂ affinity. <i>A.-</i> by Paloma Aivar (124885)

Summary of the effect of maternal immune activation on serotonin and dopamine. by Pei-Tan Hsueh (752475)

“…The cerebral 5-HT levels were significantly decreased at 5 and 8 weeks old (solid arrow), whereas the DA levels exhibited a trend towards a decrease (dotted arrow). …”

Inhibition of the mitochondrial fission decreases mtROS production. by Dong Ma (584680)

Subjects:

Incubation in Normal Saline (NS) or Plasma-Lyte (PL) rendered acidic leads to decreased endothelial dependent relaxation in intact naïve porcine saphenous veins (PSV). by Joyce Cheung-Flynn (344249)

Cocaine CPP represses MBII-52 and 5HT2CR expression in NAc. by Hongjie Chen (590575)

“…(n = 8, **P<0.01). Decreased expression of MBII-52 (C) and not 5HT2CR (D) mRNA in the NAc after cocaine-induce CPP. n = 8 and *P<0.05.…”

Transcriptional regulation of MBII-52 and 5HT2CR by chronic cocaine in NAc. by Hongjie Chen (590575)

“…<p>Repeated cocaine administration, but not acute, significantly decreased MBII-52 (A) and not 5HT2CR (B) mRNA in NAc 24 h after the final drug injection compared with saline treatments (n = 6 mice per group; *p<0.05).…”

Discovery of β‑Arrestin Biased Ligands of 5‑HT₇R by Youngjae Kim (1463614)

“…In order to identify 5-HT₇R ligands with biased agonism, we designed and synthesized a series of tetrahydroazepine derivatives <b>1</b> and <b>2</b> with arylpyrazolo moiety or arylisoxazolo moiety. …”

Discovery of β‑Arrestin Biased Ligands of 5‑HT₇R by Youngjae Kim (1463614)

“…In order to identify 5-HT₇R ligands with biased agonism, we designed and synthesized a series of tetrahydroazepine derivatives <b>1</b> and <b>2</b> with arylpyrazolo moiety or arylisoxazolo moiety. …”

Expression of cerebral serotonin related to anxiety-like behaviors in C57BL/6 offspring induced by repeated subcutaneous prenatal exposure to low-dose lipopolysaccharide by Pei-Tan Hsueh (752475)

“…We concluded that maternal immune activation induced by exposure to a low dose of LPS decreased cerebral 5-HT levels in parallel to the down-regulation of the tph2 and slc6a4 genes and in conjunction with anxiety-like behaviors in offspring.…”

Gene expression analysis of oxidative stress-related genes in A375 melanoma cells over-expressing hMp84. by Daniele Moretti (379766)

5.HT_1A binding difference between known cause of death (KCOD) controls and SIDS. by Hannah C. Kinney (10280975)

“…When SIDS is compared to all KCOD controls, the HG, NTS, and MAO show a significant mean difference in 5-HT_1A receptor binding. …”

Daily patterns of FF in a typical harmonic syllable across seven days of baseline and three days post 5-HT lesion (after the bird began singing again). by William E. Wood (491639)

The Intracellular level of FLASH decreases during apoptosis. by Song Chen (69646)

Transient over-expression of hMp84 impairs cell proliferation and stimulates cell death in HT-144 melanoma cells. by Daniele Moretti (379766)

Image1_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

Image2_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

Image3_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

CHNRI's conceptual framework showing key steps required to get from investments in health research options to decrease in burden of death, disease, or disability. by Igor Rudan (150101)