5-HT treatment modulates TGFβ3 mediated gene expression. by Philip R. Buskohl (146307)

“…<p><b>A</b>) TGFβ3 mRNA transcripts increase with physiological 5-HT (470 nM, <i>5-HT</i>), but decrease at high dose (47 µM, <i>5-HT+</i>). αSMA, RhoA, and col1α2, were not affected by physiological 5-HT dose, but were significantly downregulated with high 5-HT treatment. …”

Myoendothelial and/or endothelial gap junctions participate to the calcium and contractile responses to 5-HT. by Marie Billaud (261506)

“…B shows the mean values±S.E.M. for the effect of ^37-43Gap 27 on both the amplitude of the calcium response to 5-HT 10 µM (top) and the percentage of contraction (bottom) in whole vessels (left) and in endothelium-denuded vessels (right). …”

Revisiting the sealed heating method–heating cells in a low volume decreases nuclear Chk1. by Andrew J. Massey (239469)

Impact of 5HT stimulation on the plasma membrane density of truncated and mutant transporters. by Billow A. Ahmed (266461)

“…The transporters whose surface expressions were decreased with 5HT-stimulation, i.e., wild-type, Δ6, AAA, T₆₁₆D, and T₆₁₃D, were able to bind vimentin <i>(B)</i> and phosphovimentin <i>(D)</i>. …”

Rapid degeneration of 5-HT neurons in SERT-Cre^cre/wt Munc18-1^lox/lox mice. by Jacobus J. Dudok (338648)

“…<p>We compared the number of 5-HT cell bodies in the DRN in control and SERT-Cre^cre/wt Munc18-1^lox/lox mice at E16, E18 and P2. …”

RhoA gene expression and activity are impacted with increased intracellular 5HT. by Celeste M. Sheftel (9557588)

“…</b><i>RhoA</i> mRNA expression is significantly upregulated with FLX and 5HTP compared to controls and is significantly decreased in FLX + MDC. …”

Doubling Times (DT) and Root Mean Squared Deviation (RMSD) between EF5 positive and EF5 negative tumor time curves for pre-treatment and post-treatment A549 subcutaneous tumors. by Rehan Ali (802847)

Mean decrease in accuracy for candidate variables. by Maogui Hu (319021)

HT-CO2 significantly decreases port site metastasis. by Yuanfei Peng (3753832)

Fx controls the TNF-enhanced Ser/5-HT-promoted <i>Trypanosoma cruzi</i> uptake by U-87 MG cells and neuromediators availability. by Glaucia Vilar-Pereira (686134)

5-FU induces a decrease in the total cell number in cultures of smooth muscle cells. by Marcelo de Carvalho Filgueiras (408321)

“…We found an initial reduction of 20% at 0.01 mM up to a reduction of 70% in 10 mM of 5-FU. …”

Participants characteristics. by Sakiko Fukui (387048)

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A flow diagram of the study entry. by Sakiko Fukui (387048)

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Discovery of β‑Arrestin Biased Ligands of 5‑HT₇R by Youngjae Kim (1463614)

“…In order to identify 5-HT₇R ligands with biased agonism, we designed and synthesized a series of tetrahydroazepine derivatives <b>1</b> and <b>2</b> with arylpyrazolo moiety or arylisoxazolo moiety. …”

Discovery of β‑Arrestin Biased Ligands of 5‑HT₇R by Youngjae Kim (1463614)

“…In order to identify 5-HT₇R ligands with biased agonism, we designed and synthesized a series of tetrahydroazepine derivatives <b>1</b> and <b>2</b> with arylpyrazolo moiety or arylisoxazolo moiety. …”

Decreasing mean transistor size since 2000. by David Burg (8209752)

Comparison of mean differences in temperature decreases. by Hans-Jörg Gillmann (8460585)

Transient over-expression of hMp84 impairs cell proliferation and stimulates cell death in HT-144 melanoma cells. by Daniele Moretti (379766)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 12 covariates chosen using subjective feature selection. by Dennis Ochola (11626912)

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Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 17 covariates selected after recursive feature selection. by Dennis Ochola (11626912)

Subjects: