Design, Synthesis, and Biological Evaluation of New Peripheral 5HT_2A Antagonists for Nonalcoholic Fatty Liver Disease by Minhee Kim (1592440)

“…Here, structural modifications of pimavanserin (CNS drug), a 5HT_2A antagonist approved for Parkinson’s disease, led us to synthesize new peripherally acting 5HT_2A antagonists. …”

PGRN deletion decreased the susceptibility to invasive <i>C</i>.<i>albicans</i> infection in mice. by Jiayu Liu (3951515)

Decreased alveolar levels of TNF-α and IL-6R levels in ADAM17-null mice. by Patrick G. Arndt (351620)

Decreased cellular iron uptake increases the <i>P</i>. <i>chabaudi</i> pathogen burden. by Sarah K. Wideman (17118275)

The transcript and protein abundances of several VAC-residing proteases were decreased in Δ<i>crt</i>. by L. Brock Thornton (6808385)

Effect of decreased K8 Ser 73 or Ser431 phosphorylation on migratory ability of OSCC cells. by Hunain Alam (103978)

Loss of <i>SLC4A11</i> expression and CHED-associated <i>SLC4A11</i> mutations in hCEnC lead to decreased cell viability during tBH-induced oxidative stress. by Doug D. Chung (3611387)

Decreased naive CD4 and CD8 T cells with increased apoptosis in Rasal3-KO mice. by Ryunosuke Muro (707582)

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Mutation of Ser-489 in GC-B to alanine but not glutamate decreases CNP-stimulated guanylyl cyclase activity. by Andrea R. Yoder (165684)

HIF^C neutrophils have increased levels of apoptosis and necrosis and decreased endothelial attachment. by Kelly M. Shepardson (404375)

Activated B Cells Are Decreased in the Lungs and Spleens of IκBαM-Infected Mice by Laurie T Krug (68237)

Expression of pro-fibrotic genes of the TGFβ family is substantially decreased following AT1 receptor antagonism. by Anne-Cécile Huby (5653777)

“…Values are mean±SEM; n = 5, 9 and 13 for wild type and RenTg mice before and after irbesartan, respectively; * P<0,05 vs WT; ^# P<0,05 or ^## P<0,001 vs RenTg. …”

Mean platelet volume and neutrophil to lymphocyte ratio decrease in patients with depression with antidepressant treatment by AHMET ÖZTÜRK (8077292)

Transgenic <i>Eμ-V_H-OBF1</i> mice are immunodeficient due to decreased numbers of follicular B cells. by Alain Bordon (57422)

PKC inhibition increases intracellular cAMP and PKC activation decreases intracellular cAMP levels. by Katie M. Lowther (427408)

PI+ CD3+ T cells decrease at day 14 after IR while PI+ CD3- cells decrease at all time points. by Jordan A. Gunning (18143970)

Intervention with MLKL decreased neutrophil death and protected mice against <i>E. coli</i> pneumonia. by Qinyu Luo (13000956)

Decreased E/I synapse ratio and loss of cortico-LA synaptic plasticity in the absence of coronin 1. by Rajesh Jayachandran (542641)

“…Scale bar, 2 microns. Data shown are mean values ± SD, <i>p</i><0.01. (C) Hippocampal neurons were labeled using anti-vGLUT1 and anti-vGAT antibodies, followed by Alex Fluor 488 or 568 labeled secondary antibodies, respectively. …”

Intervention with MLKL decreased neutrophil death and protected mice against <i>E. coli</i> pneumonia. by Qinyu Luo (13000956)