UCH-L5 regulates inflammasome activity in chicken macrophages. by Evangel Kummari (719636)

“…<p><b>(A-B). UCH-L5 overexpression leads to reduced cell viability in infected as well as uninfected HD11 macrophages, which depends on its catalytic activity.…”

Inflammation Regulates TMPRSS6 Expression via STAT5 by Delphine Meynard (87311)

“…The downregulation of Tmprss6 by inflammation in mice is not dependent on the Bmp-Smad pathway but occurs through a decrease in Stat5 phosphorylation. Moreover, Stat5 positively regulates Tmprss6 expression directly by binding to a Stat5 element located on the Tmprss6 promoter. …”

AKT regulates UGCG expression via epigenomic alterations. by Mohammad Nafees Ansari (22232505)

“…(<b>M</b>) Immunoblot reveals a decrease in phosphorylation of KDM5A on treatment of MCF-7_ZFX^OE cells with AKT inhibitor MK2206. …”

UCH-L5 regulates inflammasome activity in human macrophages. by Evangel Kummari (719636)

“…<p><b>(A). Exposure of THP-1 macrophages to b-AP15 inhibitor leads to decrease in IL-1β upon inflammasome activation.…”

Stereological parameters: Surface density and total surface of alveolar septa as well as septal thickness during postnatal development. by Franziska Roeder (18155978)

Primary cultures of oral fibroblasts from newborn rats incubated for 90 min in medium containing GSNO (a–d) or GSNO-free (e–h). by Maria Adriana Skeff (670466)

Related to Fig 4. by Mohammad Nafees Ansari (22232505)

“…(<b>C</b>) Results from qRT-PCR (mean ± SEM, <i>n</i> = 4) show a decrease in <i>UGCG</i> expression in BT-474_ZFX^OE cells on AKT inhibition by MK2206 (4 μM). …”

Results for the unimodal spatial-discrimination task. by Fangfang Hong (11707989)

Comparison of 5′-reference miRNA and 5′-shifted isomiR expression levels among MIN6 cells, human beta cells, and human islet. by Jeanette Baran-Gale (456176)

“…The y-axis depicts the Log10 of the average read count per million for each 5′-reference miRNA in each sample. (<b>B</b>) The x-axis shows the highly expressed 5′-shifted isomiRs ordered from left to right by decreasing fold-difference between primary human beta cells and MIN6 cells. …”

NAD⁺ metabolites regulate skin oxidative stress and inflammation. by Francisco J. Martínez-Morcillo (11663364)

Accelerated Immunodeficiency by Anti-CCR5 Treatment in HIV Infection by Ariel D. Weinberger (169848)

“…The model shows that the R5-to-X4 switch occurs as CD4⁺ T cell activation levels increase above a threshold and as CD4⁺ T cell counts decrease below a threshold during late-stage HIV infection. …”

Replacement of intra- and extracellular chloride for D-gluconate eliminated statistically significant decreases in GLT-1 stoichiometric current and the current/flux ratio in 100–30... by Anatoli Y. Kabakov (729047)

The ratio of absolute minimal dV/dt to maximal dV/dt is affected by the overlap level of Na⁺ and K⁺ currents. by Yuguo Yu (172221)

“…The ratio γ (defined as the ratio of absolute minimal dV/dt to maximal dV/dt) increases as a function of temperature for both classical HH neuron and cortical neuronal models, owing largely to the decrease in overlap of Na⁺ and K⁺ currents with increases in temperature. …”

Pathological pathways associated with SARS-CoV-2 infection in hamsters and COVID-19 patients were upregulated in hamsters challenged with SARS-CoV-2. by Malika Aid (7303874)

“…Shown are genes that are increased (red gradient) or decreased (blue gradient) at 4 dpi in sham compared to naïve control animals that were reported in a published SARS-Cov-2 hamsters study [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1009990#ppat.1009990.ref006" target="_blank">6</a>]. …”

CD43^-/- septic mice exhibit decreased frequencies of apoptotic CD4⁺ and CD8⁺ naïve T cells as compared to WT septic mice. by Katherine T. Fay (2576998)

“…B) CD43^-/- septic mice exhibited a decreased frequency of apoptotic naïve CD4⁺ T cells, defined as 7-AAD⁺ Annexin V⁺ CD44^LO CD62L^HI CD4⁺ cells, compared to WT septic mice (11.8±1.6 vs 18.8±1.3, p = 0.002. …”

Changes in the leaf contents of total phenols and 5-caffeoylquinic acid. by José C. Ramalho (493978)

“…<p>Values of total phenols (mg GAE g^-1 dw), and 5-caffeoylquinic acid (5-CQA) along the entire experiment for Apoatã, Icatu, and Obatã genotypes, under well-watered (WW), mild drought (MD) and severe drought (SD) conditions, and submitted to temperature control conditions (25/20 ^oC), during the gradual temperature decrease (18/13 ^oC), at the end of the acclimation period (13/8 ^oC), after 3 chilling cycles (3x13/4 ^oC), after 7 days under rewarming conditions (7x Rec Cold), and after a further 7 days period under rewatering conditions (7x Rec Drought).…”

Comparison of WT and mutant SHC014-CoV S ectodomains. by Alexandra L. Tse (20235212)

“…Area under the curve represents protein expression. A835D-containing variants exhibit a large decrease in protein expression relative to the WT and F294L SHC014-CoV spikes. …”

CBD (30 mg/kg, n = 7–9 animals/group) and HU-101 (10 mg/kg, n = 9–10 animals/group) decreased the number of buried marbles in the MBT. by Aviva Breuer (3153021)

NeuroD1 suppresses ferroptosis by upregulating GPX4. by Ping Huang (30439)

Presentation 1_Case report: Exploring efficacy of tofacitinib in modulating interferon response in five case of anti-MDA5+ dermatomyositis with interstitial lung disease.pdf by Jie Zhao (49409)

“…<p>A case report highlights the challenges faced in managing a 66-year-old Chinese woman diagnosed with anti-MDA5 antibody-positive dermatomyositis (MDA5-DM) complicated by rapidly progressive interstitial lung disease (RP-ILD). …”