Design, Synthesis, and Biological Evaluation of New Peripheral 5HT_2A Antagonists for Nonalcoholic Fatty Liver Disease by Minhee Kim (1592440)

“…Here, structural modifications of pimavanserin (CNS drug), a 5HT_2A antagonist approved for Parkinson’s disease, led us to synthesize new peripherally acting 5HT_2A antagonists. …”

MEK5 expression decreases ER signaling and confers endocrine resistance. by James W. Antoon (444010)

Decreased expression of HATL5 mRNA and protein in human carcinomas. by Gregory S. Miller (519005)

Impact of 5HT stimulation on the plasma membrane density of truncated and mutant transporters. by Billow A. Ahmed (266461)

“…<p>CHO cells expressing truncated or mutant forms of transporter were either directly <i>(A and B)</i> or after stimulated with 100 μM 5HT <i>(C and D)</i> subjected to the cell surface biotinylation assays. …”

Data Sheet 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.pdf by Evan Fuini (21224939)

Table 4_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx by Evan Fuini (21224939)

Data Sheet 2_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.docx by Evan Fuini (21224939)

Table 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.docx by Evan Fuini (21224939)

Table 5_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx by Evan Fuini (21224939)

Table 2_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx by Evan Fuini (21224939)

Table 3_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx by Evan Fuini (21224939)

Flibanserin’s neuroprotective effects are 5-HT_1A receptor-mediated. by Aaron S. Coyner (2889722)

“…A 6 mg/kg dose of flibanserin in 5-HT_1A knockout mice (5-HT1A KO + 6 mg/kg Flibanserin, <i>red</i>) resulted in average receptor plus thickness that was not significantly different from vehicle-injected and naïve mice. …”

DPI, NAC and resveratrol decrease lipolysis. by Sarah A. Krawczyk (172699)

ETHE1-p.Arg163Gln and p.Arg163Trp are folded but have decreased stability. by Bárbara J. Henriques (627180)

Data_Sheet_1_hsa-miR-3177-5p and hsa-miR-3178 Inhibit 5-HT1A Expression by Binding the 3′-UTR Region in vitro.doc by Xue Wu (317735)

“…Dual luciferase reporter assay and Western Blot were used to confirm the effect of miRNA mimics and inhibitors on endogenous 5-HT1A receptors. In all cell lines, gene expression of the −17 bp to +443 bp fragment containing the complete sequence of the 3′-UTR region was significantly decreased, although mRNA quantification was not different. …”

Human 5-HT₄-based RASSLs. by Wei Chun Chang (43479)

“…<p>A signal peptide and the FLAG epitope were added to the N-terminus of the human 5-HT₄ receptor. …”

5-HT₇Dro knock-down decreases frequency of courtship behaviors. by Jaime Becnel (218896)

“…When compared with the parental lines 5-HT₇-Gal4 (Gal4) and UAS-sym-5-HT₇-dsRNA (UAS), the frequency of licking, curling and copulation attempts was significantly decreased. …”

Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

The catalase enzyme response of <i>A</i>. <i>albopictus</i> larvae decreased (1.5-fold) in response to <i>M</i>. <i>robertsii</i>-derived copper nanoparticles. by Perumal Vivekanandhan (4863484)

Rhox5 decreases UNC5C expression. by Mayumi Sugimoto (151133)