Chronic, sublethal neonicotinoid exposure decreases cumulative weight gain and cluster size of honey bee colonies. by Sarah C. Wood (4730634)

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Su(H) and RBPJ AOS variants decrease DNA binding. by Ellen K. Gagliani (11478756)

Vasopressin decreases EPSPs in CA2 after LTP induction. by Magda Chafai (295116)

“…Vasopressin (AVP 10 nM; 1 min) applied during LTP transiently decreased the EPSP amplitude. …”

Hypoxia dramatically decreased cGMP in cultured porcine retina. by Lorena Olivares-González (3352898)

Berberine decreases IBMX- and FSK-induced CRE luciferase activity. by Juan Zhang (48597)

c-Abl inhibition decreases ABCB1 expression and activity. by Jonathan T. Sims (278652)

HDAC inhibition by TSA decreases SREBP2 proteolytic cleavage. by Maria João Nunes (160499)

GSK-3β inhibition or silencing decreases reporter activity. by Rong Guo (50063)

Calyculin A-induced decrease of tyrosine-monophosphorylated ERK2 at high cell density. by Noriyuki Kawabata (3391739)

Mean Decrease in Margin (MDM) variable importance. by Yuliya V. Karpievitch (259460)

HC-070 decreases anxiety in a standard EPM. by Stefan Just (4811358)

Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant. by Esther Magdalena Marquez-Lona (4183126)

“…The mean ± SEM rate of Suc-LLVY-AMC cleavage is decreased in the <i>myc-rpt6-S119A</i> mutant compared to the WT and <i>myc-rpt6-S119D</i> strains. …”

Cell adhesion was decreased by simvastatin and benznidazole during <i>Trypanosoma cruzi</i> infection. by Carolina Campos-Estrada (403914)

Chemical Inhibition of eEF1A-1 Peptide Elongation Activity Decreases Palmitate-Induced Cell Death. by Alexandra M. Stoianov (759321)

Silencing <i>cullin-1/5</i> decreased mRNA and protein expression of NF-κB dependent cytokines. by Attinder Chadha (11414273)

Subjects:

Real-time PCR confirmation of randomly selected genes whose expression levels were either increased (red) or decreased (green) by a specific endoxifen concentration. by John R. Hawse (227611)

“…Darkly shaded bars depict relative fold changes from E₂ (10 nM), TAM (300 nM), 4HT (7 nM) and NDT (700 nM) treated cells (combo/dashed line) as detected by microarray analysis while lightly shaded bars depict fold change as detected by RT-PCR analysis. …”

Concentrations of 5-HT and 5-HIAA in brain tissue. by Thibault Renoir (348572)

“…Both 5-HT and 5-HIAA concentrations were decreased in the hippocampus (A/B), the cortex (C/D) and the striatum (E/F) in female HD mice when compared to WT animals. …”

Inducing proteotoxic stress in 5-HT neurons does not recapitulate a <i>Minute</i> phenotype. by Lisa Patricia Deliu (13570709)