HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human corona... by Martine Auclair (8350998)

“…</p><p>Results</p><p>Dolutegravir reduced inflammation by decreasing NFκB activation and IL-6/IL-8/sICAM-1/sVCAM-1 secretion, as did maraviroc with a milder effect. …”

Discovery of <i>N</i>‑[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl... by John S. Debenham (2295976)

“…Mouse and rat studies showed hematological changes with elevations of plasma EPO and circulating reticulocytes following single oral dose administration, while 4-week q.d. po administration in rat elevated hemoglobin levels. A major focus of the optimization process was to decrease the long half-life observed in higher species with early compounds. …”

Annual average incidence rates of human rabies in provinces from 2004–2020. by Weiwei Meng (304234)

Developing a continuous adjustment factor for dry matter intake of gestating and lactating ewes by Sarita Bonagurio Gallo (6677612)

Temporal Trends of Great Lakes Legacy Contaminants: Ecological and Biological Considerations Applying the Age-Trend Model by James J. Pagano (2043490)

“…Our research revealed that select legacy contaminant groups (∑PCBs, ∑DDTs, ∑chlordanes, and ∑5PBDEs) have similar <i>t</i>_1/2 and <i>k</i>₂ values across the Great Lakes, with the exception of both Lake Erie sites and the Lake SuperiorKeweenaw Point site. …”

Table_1_BNT162b2 COVID-19 vaccination in children alters cytokine responses to heterologous pathogens and Toll-like receptor agonists.docx by Andrés Noé (3620534)

“…Samples from 29 children, aged 5-11 years, before and 28 days after a second BNT162b2 vaccination were analysed (V2 + 28). …”

DataSheet_1_BNT162b2 COVID-19 vaccination in children alters cytokine responses to heterologous pathogens and Toll-like receptor agonists.zip by Andrés Noé (3620534)

“…Samples from 29 children, aged 5-11 years, before and 28 days after a second BNT162b2 vaccination were analysed (V2 + 28). …”

Table_1_BNP as a New Biomarker of Cardiac Thyroid Hormone Function.DOCX by Kaihao Wang (9100646)

“…Myocardial BNP mRNA was increased 2.5-fold in Hypo rats and its expression was decreased to normal values by 14 days of T3 treatment. …”

Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder by Comfort A. Boateng (3617120)

“…Off-target antagonism of 5-HT_2A or 5-HT_2B may also contribute to these effects. …”

Fat mass loss survival curve by sex during inpatient treatment. by Domingos L. S. Rios (20496173)

Size effects on dislocation starvation in Cu nanopillars: a molecular dynamic simulations study by G. Sainath (17069218)

“…Furthermore, we define the dislocation starvation strain and based on this, it has been shown that the contribution of the dislocation starvation to the total plastic strain decreases from 70% in small-sized nanopillars to below 5% in large-sized pillars. …”

Dephosphorylation of AMPK substrate i.e. acetyl CoA carboxylase (ACC) initiates neuritogenic effect of SIM. by Varshiesh Raina (457377)

“…SIM led to a significant (<i>p</i> < 0.05^*) increase in pACC (Ser-79) levels at 2 hrs which was followed by a gradual decrease. …”

Developmental and Neurobehavioral Toxicity of Hexaphenoxycyclotriphosphazene: Implications for Its Safety as a Flame-Retardant Alternative to Triphenyl Phosphate by Ruobing Bai (4860043)

“…HPCTP caused dose-dependent depression-like behaviors (hypoactivity, light-zone avoidance) through suppression of serotonin 1A (5-HT₁A) signaling, supported by decreased <i>htr1aa</i> expression and serotonin levels and partially rescued by the 5-HT₁A receptor agonist 8-OH-DPAT. …”

Background compensation by coherent feedback in the scheme of Fig 13. by Melissa Nygård (15374507)

Supplementary Material for: Successful Chemotherapy for Diffuse Cystic Lung Metastases during Targeted Therapy with Osimertinib in a Patient with Non-small-cell Lung Cancer: Litera... by Matsukida A. (17340805)

<i>Salmonella</i> A1-R targeting and efficacy on the melanoma PDOX model. by Mako Yamamoto (577524)

“…Tumor size of the <i>Salmonella</i> A1-R-treated group was significantly decreased compared with the untreated control group. …”

Post-burn cardiac function <i>in vivo</i> and <i>ex vivo</i> in a Langendorff preparation. by Rong Xiao (130656)

“…The left ventricular systolic pressure (LVSP) and mean arterial pressure (MAP) decreased from 1 h to 3 h post-burn and continued to decline in the following time points. …”

<i>F. novicida</i> deletion mutants of a putative transglutaminase are severely attenuated in virulence and growth. by Madeleine G. Moule (243057)

“…The difference between the mean number of CFUs of wild-type and FTN_0869 has decreased at every timepoint, with only a 2.9-fold increase in wild-type bacteria compared to FTN_0869 bacteria at 24 hours, 6-fold more bacteria in U112 infected flies at 48 hours, and only 4-fold more U112 bacteria than FTN_0869 bacteria at 72 hours. …”

Anthropogenic soil acidification severely imperils microbial diversity and functionality: A global synthesis by d xz (16960341)

“…Notably, nitrogen-induced acidification significantly reduces microbial richness, Shannon index, biomass, and functionality by 5.1%, 3.1%, 4.1%, and 5.1%, respectively. Meanwhile, acid addition decreases microbial biomass and functionality by 9.4% and 15%, respectively. …”

A σ^E-Mediated Temperature Gauge Controls a Switch from LuxR-Mediated Virulence Gene Expression to Thermal Stress Adaptation in <i>Vibrio alginolyticus</i> by Dan Gu (2191075)

“…An <i>rpoE</i> null <i>V</i>. <i>alginolyticus</i> mutant was unable to adapt to various stresses and was survival-deficient in fish. …”