5-HT- induced mitochondrial ROS inhibits <i>P</i>. <i>berghei</i> infection. by Li Gao (131516)

Effect of 5-HTR blockade on the relationship between error rate and reaction time in the reward-size task. by Yukiko Hori (299784)

Subjects:

Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice by Guillaume P. Dugué (620333)

“…<i>In vivo</i>, the photoactivation of dorsal raphe serotonergic neurons gave rise to a prominent light-evoked field response that displayed some sensitivity to a 5-HT1A agonist, consistent with autoreceptor inhibition of raphe neurons. …”

Apoptosis inhibitor prevented the decrease of IIL ESP-induced TJs expression and alleviated barrier disruption of Caco-2 monolayer. by Qi Qi Lu (17721401)

Subjects:

Systemic role of the peripheral 5HT. by Igor Erjavec (2265613)

“…Elevated 5HT bidirectionally influences the plasma insulin level (green-red arrow) and induces the hyperthrophy of pancreatic β-cells (dashed arrow), leading to type 2 diabetes with an increased plasma glucose, insulin resistance, glucose intolerance, visceral fat volume and decreased muscle strength. …”

Occupancy estimation. by Yukiko Hori (299784)

Subjects:

Fluorescence rise response of inverse-pericam and IP2.0 to a stepped decrease in Ca2+ by Sayuri Hara-Kuge (4954180)

Prenatal treatment decreases proliferation and increases apoptosis in small intestine. by Fátima Ramalhosa (3095712)

“…(B) Proliferation rate is decreased within the crypts in <i>iuGC</i> rats, n = 3, 4, 5 CTR and n = 3, 6, 3 <i>iuGC</i>. …”

<i>Gng5^−/−</i> mutants have decreased cell proliferation and survival. by Anne M. Moon (134982)

Respiratory network responses to systemic 5-HT_2AR and 5-HT_2BR activation. by Marcus Niebert (183419)

“…Statistical analysis (paired t-test) is denoted in the panels on the right side. (<b>A</b>–<b>C</b>) Action of 5-HT_2AR and 5-HT_2BR ligands in the perfused brainstem preparation. …”

Genotype frequencies of the polymorphisms <i>rs1799971</i> (OPRM1), <i>rs6296</i> (5-HT_1A) and the triallelic 5-HTT for the whole group, as well as fibromyalgia (FM) pat... by Jeanette Tour (10790855)

Step Analysis. by Mengnan Wu (769253)

Effect of 2%, 4%, and 6% HQ cream on hippocampal 5-HT level and 5-HT_{1A /1B} receptor expression. by Huali Wu (349567)

“…<p>(A) HQ decreases hippocampus 5-HT level in a dose-dependent manner. …”

Additional Analysis of visually induced calcium transients in Fig 5. by Maureen M. Sampson (9322886)

“…<p>Visually induced calcium transients were recorded in flies expressing L2-split-GAL4>GCaMP6f as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g005" target="_blank">Fig 5</a>. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

GXM decreases the trans-endothelial electrical resistance (TEER) and transmigration of <i>C</i>. <i>neoformans</i> through HBECs in a blood brain barrier (BBB) model. by Hiu Ham Lee (15374677)

Normalized pressure pain thresholds (PPTs) (mean ± SEM) at start, middle, end and 5 minutes after a standardized tourniquet test. by Jeanette Tour (10790855)

Matrix crosslinking decreases cell migration persistence. by Michael Pamonag (12295175)

<i>iuGC</i> animals at 3 and 8 months old have a decreased GI transit. by Fátima Ramalhosa (3095712)