Decreased biofilm formation in the Δ<i>tad123</i> mutant cells. by Tra-My Duong-Nu (7300970)

1,25D and phosphate treatment of Ocy454 cells decreases expression of genes implicated in perilacunar matrix resorption. by Ye Yuan (531126)

The G215S mutation decreases packaging of N and growth in primary differentiated human bronchial cells. by Hannah C. Kubinski (21213168)

Additional Analysis of visually induced calcium transients in Fig 6. by Maureen M. Sampson (9322886)

“…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …”

LuxR G37V has decreased DNA-binding activity. by Chelsea A. Simpson (9579303)

Serotonin modulates L2 neuron visually induced calcium transient kinetics. by Maureen M. Sampson (9322886)

“…Light or dark stimuli (A, middle panel, white and black vertical bars respectively) were flashed at random every 5 s for 6 min. …”

WT data of set A398E/V and set M1425V/I pooled for better comparison. by Yousra El Ghaleb (22075892)

Subjects:

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

ERK signaling and expression of β-arrestin2 in Ang II–induced mouse AAA models as well as in WT or Klf5^−/− VSMCs. by Dong Ma (584680)

Subjects:

Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

Subjects:

Loss of Rtr1 activity leads to decreased RNAPII occupancy at <i>SNR</i> genes and shortened <i>SNR</i> transcripts. by Jose F. Victorino (8595885)

Loss of <i>SLC4A11</i> expression in hCEnC leads to decreased cell barrier function. by Doug D. Chung (3611387)

Cardiac function assessed by echocardiography in Ang II–infused young (3 months) or old (18 months) WT and smcKlf5^−/− mice. by Dong Ma (584680)

Subjects:

Overexpression of CCP5A and CCP5B induced flagellum length decrease and cell cycle defects. by Louise Basmaciyan (4576624)

Decreased thrombin activity levels in PAR KO following 24 hours following ischemia. by Efrat Shavit-Stein (3186678)

“…<p>(A) Total thrombin activity is significantly decreased in PAR1 KO compared to WT mice (t-test). …”

STAT6-driven immunity decreases <i>N</i>. <i>brasiliensis</i> reproductive output and survival within host. by Annabel A. Ferguson (17616286)

Nrf2 activation decreases PMN ROS production in response to zymosan. by Doumet Georges Helou (7255823)

RhoA gene expression and activity are impacted with increased intracellular 5HT. by Celeste M. Sheftel (9557588)

“…<p><b>A.</b><i>RhoA</i> mRNA expression is significantly upregulated with FLX and 5HTP compared to controls and is significantly decreased in FLX + MDC. …”

TSLPR deficient mice show decreased AHR upon HDM exposure. by Latifa Koussih (326043)