The hepatic cellular environment is altered with PLD inhibitors. by Karen M. Henkels (3350273)

“…Xenotransplanted MDA-MB-231 cells in the presence of vehicle, FIPI or VU0155072-2, respectively, and no xenotransplantation in the presence of vehicle. (<b>A-D</b>) Scale bar = 50 μm. (<b>E-Q</b>) Scale bar = 200 μm. …”

Correlations between soil chemical properties. by Fengzhen Fu (17720636)

Differences in mean scores of upper extremity performance in all five accelerometer-derived variables across four time points- pre-HABIT, post-HABIT, 3-month, and 6-month post-HABI... by Shailesh S. Gardas (20490020)

Experimental setup of H9c2 cells exposed to normoxia/hypoxia. by Frederik Abel (8452101)

S1 Graphical abstract - by Jennifer Astley (19859612)

“…</p><p>Results</p><p>Population structure did not appear to affect the timeline of elimination targets and screening individuals over the age of 30 at a high (50% per year) coverage could bring forward achievement of the incidence elimination target by four years compared to baseline (approximately 6% per year). …”

The small molecule Scaff10-8 inhibits the interaction of the DH domain of AKAP-Lbc and RhoA. by Katharina Schrade (4801266)

“…(B) In the HTRF from (A), Scaff10-8 inhibited the interaction of AKAP-Lbc/DHPH and RhoA with an IC₅₀ = 34.1 μM whereas Scaff10-59 did not (example of a negative Scaff10 derivative). …”

Mass spectrum of 7-MH. by Juthamart Maneenet (15999769)

“…This study evaluated the anti-cancer potential of 7-methoxyheptaphylline (7-MH), a carbazole alkaloid from <i><i>Clausena harmandiana</i></i>, against pancreatic cancer cells (PANC-1) and developed an environmentally sustainable extraction methodology using ultrasonic-assisted extraction (UAE). 7-MH demonstrated selective cytotoxicity against PANC-1 cells with preferential activity under nutrient deprivation conditions (PC₅₀ = 4.54 μM) compared to nutrient-rich conditions (IC₅₀ = 46.84 μM). …”

ANOVA for 7-MH yield. by Juthamart Maneenet (15999769)

“…This study evaluated the anti-cancer potential of 7-methoxyheptaphylline (7-MH), a carbazole alkaloid from <i><i>Clausena harmandiana</i></i>, against pancreatic cancer cells (PANC-1) and developed an environmentally sustainable extraction methodology using ultrasonic-assisted extraction (UAE). 7-MH demonstrated selective cytotoxicity against PANC-1 cells with preferential activity under nutrient deprivation conditions (PC₅₀ = 4.54 μM) compared to nutrient-rich conditions (IC₅₀ = 46.84 μM). …”

Raw images of Western blot experiment. by Juthamart Maneenet (15999769)

“…This study evaluated the anti-cancer potential of 7-methoxyheptaphylline (7-MH), a carbazole alkaloid from <i><i>Clausena harmandiana</i></i>, against pancreatic cancer cells (PANC-1) and developed an environmentally sustainable extraction methodology using ultrasonic-assisted extraction (UAE). 7-MH demonstrated selective cytotoxicity against PANC-1 cells with preferential activity under nutrient deprivation conditions (PC₅₀ = 4.54 μM) compared to nutrient-rich conditions (IC₅₀ = 46.84 μM). …”

Expression of PerRA and PerRB in <i>L</i>. <i>interrogans</i> wild-type and mutant strains. by André A. Grassmann (11141592)

Image_3_IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer’s Disease Transgenic Mouse Model.TIF by Mona Sohrabi (9082586)

Image_1_IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer’s Disease Transgenic Mouse Model.TIF by Mona Sohrabi (9082586)

Image_2_IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer’s Disease Transgenic Mouse Model.TIF by Mona Sohrabi (9082586)

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

Variation law of AE events rate of sandstone under different freeze-thaw cycles at a loading rate of 0.05 mm/min. by Wenyu Lv (20139458)

Variation law of AE events rate of sandstone under different freeze-thaw cycles at a loading rate of 0.05 mm/min. by Wenyu Lv (20139458)

Climate complexity in the migratory cycle of <i>Ammodramus bairdii</i> by Alexander Peña-Peniche (5687786)

“…A continuous and alarming decrease of its populations has been observed over the last 50 years, and studying its seasonal distribution and associated climatic niches could help improve strategies for its conservation. …”

miR-27a protects human mitral valve interstitial cell from TNF-α-induced inflammatory injury via up-regulation of NELL-1 by Honglei Chen (125181)

Vitamin A deficiency indicating as low expression of LRAT may be a novel biomarker of primary hypertension by Xiaohua Liang (535684)

“…<p>Vitamin A (VA) deficiency triggers many diseases and is a worldwide nutrition problem. …”

Early reduction in total cholesterol to high-density lipoprotein cholesterol ratio predicts hydroxychloroquine efficacy in treating IgA nephropathy by Yaotong Shi (19511899)

“…</p> <p>Patients in the high TC/HDL-C decline rate group with ≥50% decrease in proteinuria from baseline experienced a significant improvement during the follow-up. …”