Data_Sheet_1_Neurobiological outcomes of cognitive behavioral therapy for obsessive-compulsive disorder: A systematic review.docx by Andrea Poli (3623465)

“…</p>Results<p>We obtained 26 pre-post CBT treatment studies performed using different neurobiological techniques, namely functional magnetic resonance imaging (fMRI), Positron emission tomography (PET), regional cerebral blood flow (rCBF), 5-HT concentration, magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), Electroencephalography (EEG). …”

Supplementary Material for: Possible Association of <i>SLC22A2</i> Polymorphisms with Aspirin-Intolerant Asthma by Park T.-J. (4124089)

“…Recently, SLC22A2-mediated uptake inhibition by several nonsteroidal anti-inflammatory drugs and decreased SLC22A2 transport activity by its genetic variants have been elucidated in asthma. …”

CEP Biomarkers as Potential Tools for Monitoring Therapeutics by Kutralanathan Renganathan (465207)

“…AL-8309A is a serotonin 5-HT_1A receptor agonist.</p> <p>Methods</p><p>Albino rats were dark adapted prior to blue light exposure. …”

Image1_Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling.pdf by Fan Wu (43375)

Depletion of viral IE2 in late infection does not affect viral long promoter transcription. by Qiaolin Hu (8677473)

“…Viral TSSs that exhibited a ≥ 2-fold increase or ≥50% decrease in strength due to IE2 depletion (demarcated by hatched lines) were classified as IE2-responsive and are indicated by green dots. …”

Data_Sheet_1_Excess Mortality in Italy During the COVID-19 Pandemic: Assessing the Differences Between the First and the Second Wave, Year 2020.PDF by Maria Dorrucci (252694)

“…The models were also applied to estimate all-cause excess deaths “not directly attributable to COVD-19”, i.e., without a previous COVID-19 diagnosis. During the first wave (25th February−31st May), we estimated 52,437 excess deaths (95% CI: 49,213–55,863) and 50,979 (95% CI: 50,333–51,425) during the second phase (10th October−31st December), corresponding to percentage 34.8% (95% CI: 33.8%–35.8%) in the second wave and 31.0% (95%CI: 27.2%–35.4%) in the first. …”

Somatic <i>HTT</i> CAG instability differs between B6.<i>Hdh^Q111</i>^/+ and 129.<i>Hdh^Q111</i>^/+ mice. by Ricardo Mouro Pinto (207712)

Data_Sheet_2_Excess Mortality in Italy During the COVID-19 Pandemic: Assessing the Differences Between the First and the Second Wave, Year 2020.PDF by Maria Dorrucci (252694)

“…The models were also applied to estimate all-cause excess deaths “not directly attributable to COVD-19”, i.e., without a previous COVID-19 diagnosis. During the first wave (25th February−31st May), we estimated 52,437 excess deaths (95% CI: 49,213–55,863) and 50,979 (95% CI: 50,333–51,425) during the second phase (10th October−31st December), corresponding to percentage 34.8% (95% CI: 33.8%–35.8%) in the second wave and 31.0% (95%CI: 27.2%–35.4%) in the first. …”

Summary of the effects of deletion of Y2 receptors on non-NPY-ergic or NPY-ergic neurons in the brain. by Yan-Chuan Shi (153820)

“…However, Y2 receptors on NPY-ergic neurons in the amygdala induce anxiogenic effects <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0011361#pone.0011361-Tasan1" target="_blank">[50]</a>, likely due to decreased endogenous NPY-ergic action <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0011361#pone.0011361-Heilig1" target="_blank">[56]</a>. …”

Presentation 1_Changes to inflammatory markers during 5 years of viral suppression and during viral blips in people with HIV initiating different integrase inhibitor based regimens... by Nicholas T. Funderburg (9422033)

“…Additional samples from PWH who experienced a viral blip (n=44, defined as a single HIV-1 RNA >50c/mL) were also analyzed and paired with the most recent available suppressed sample before the blip. …”

Influence of <i>k</i>₁ on the homeostatic behavior of the m7 ping-pong controller when <i>E</i>₁ binds first to free enzyme <i>Ez</i>. by Qaiser Waheed (5095328)

“…(c) A decrease of <i>k</i>₆ from 5.0 to 1.0 while <i>k</i>₁ is kept at 100.0 gives a general improvement of the homeostatic performance of the ping-pong controller, except for the higher end <i>k</i>₅ range between 900–1000, where <i>A</i>_<i>ss</i> becomes constant (indicated by the red circle). …”

Wet laboratory validation of in silico results. by Patrick Baum (235495)

“…IL-6 secretion was analyzed as surrogate marker for pro-inflammatory processes. A: High content screen images of HaCaT cells treated with increasing concentrations (3.2 nM – 50 µM) of Ex1 and BI5 including DMSO (negative control) or 100 µM Valinomycin and 10 µM Chloroquine (positive control) for 24 h. …”

Inter-county mobility patterns reflect social distancing and travel restrictions. by Hengfang Deng (7003667)

“…While the data only lost a small number of devices, the two measures both plummeted more than 50% within two weeks before recovering.…”

Supplementary Material for: Polypharmacy and the Progression of Chronic Kidney Disease: Korean Cohort Study for Outcome in Patients with Chronic Kidney Disease by Min H.K. (10922121)

“…Polypharmacy was defined as taking 6 or more medications at the time of enrollment; renal events were defined as a ≥50% decrease in kidney function from baseline values, doubling of the serum creatinine levels, or initiation of renal replacement treatment. …”

hERG Potassium Channel Blockage by Scorpion Toxin BmKKx2 Enhances Erythroid Differentiation of Human Leukemia Cells K562 by Jian Ma (170138)

“…</p> <p>Principal Findings</p><p>The hERG potassium channel blockage by a new 36-residue scorpion toxin BmKKx2, a potent hERG channel blocker with IC₅₀ of 6.7±1.7 nM, enhanced the erythroid differentiation of K562 cells. …”

Data_Sheet_1_Physiological, transcriptomic, and metabolic analyses reveal that mild salinity improves the growth, nutrition, and flavor properties of hydroponic Chinese chive (Alli... by Ning Liu (168279)

“…However, a higher level of salinity (25 or 50 mM NaCl) resulted in growth inhibition, yield reduction, and leaf quality deterioration of hydroponic chive plants. …”

KMM cells do not require glucose for proliferation, survival and formation of colonies in Softagar. by Ying Zhu (90057)

“…<p>(<b>A</b>). KMM cells do not require glucose for proliferation. …”

Presentation_1_Physiological, transcriptomic, and metabolic analyses reveal that mild salinity improves the growth, nutrition, and flavor properties of hydroponic Chinese chive (Al... by Ning Liu (168279)

“…However, a higher level of salinity (25 or 50 mM NaCl) resulted in growth inhibition, yield reduction, and leaf quality deterioration of hydroponic chive plants. …”

Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency by Arne Björn Potthast (4529689)

“…</p><p>Results</p><p>We observed a significant decrease in cellular levels of all three sirtuins at the activity, protein and transcriptional level (by 15% to 50%) in COX-deficient cells. …”

Waist-to-Height Ratio and Cardiovascular Risk Factors among Chinese Adults in Beijing by Li Cai (3899)

“…AUCs for the relationships between anthropometric indices and the three outcomes were larger in women than in men, and tended to decrease with age. Optimal cutoffs for WHtR were 0.51–0.53 and 0.48–0.50 in men and women, respectively. …”