Search alternatives:
ht decrease » _ decrease (Expand Search), nn decrease (Expand Search), step decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
ht decrease » _ decrease (Expand Search), nn decrease (Expand Search), step decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Analysis of tumour vasculature with the addition of more HT groups.
Published 2020“…The vasculature becomes less evident in the treated groups, with decreasing numbers of stained blood vessels. Images were taken at a 20x objective lens, and the scale bar denotes ~50μm. …”
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Decreased clonogenic capacity of U87MG and U251MG glioma cells dependent on SHG-44 concentration.
Published 2025“…<b>(B)</b> A significant decrease in the proliferative clonal capacity of U251MG colonies was observed with 50ΜM and 100ΜM SHG-44 treatment. …”
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Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis.
Published 2021“…<i>n =</i> 5, data are mean ± SD. *<i>p</i> < 0.05. Uncropped western blots are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s016" target="_blank">S1 Raw Images</a>, and numerical data for all graphs are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s014" target="_blank">S6 Data</a>. …”
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Decreased phosphorylation of EIF2α underlies the impairment of arsenite-induced SG formation in LSM12-depleted cells.
Published 2020“…<p>(A) LSM12 depletion does not suppress the SG assembly under sorbitol-induced osmotic stress. …”
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Capsaicin, pyridoxine, vincristine sulfate and ionomycin significantly decreased axon length ratio but only pyridoxine had no impact on neurotoxicity.
Published 2024“…At a lower dose, 50 μM Pyr, did not induce significant change in axon length ratio over time and between PBS control in both female and male rat DRGs. …”
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