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121
Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters
Published 2016“…Two batches of sensors were tested in this work: i) sensors based on graphene only, and ii) sensors based on graphene and percolating films of Au nanoclusters, each has a thickness of 5 nm. …”
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122
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
Published 2020“…We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …”
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123
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation-contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l-type Ca2+ (Cav1.2), sodium (NaV1.5) and potassium (KV7.1) channels. …”
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124
Tailoring optical absorption in silicon nanostructures from UV to visible light: A TDDFT study
Published 2016“…(ii) The exciton binding energy is seen to decrease by approximately 45% from 0.67 eV to about 0.3 eV with length increase, for a nanostructure with a cross-section diameter of approximately 12 Å. …”
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Evaluating the effect of glycaemic control, blood pressure, lipid profile and diabetes duration on developing diabetes complications and its progression
Published 2018“…Patients with two complications had the highest HbA1c level (8.5 ± 2%) (P=0.035). There were no significant differences in the BP and lipid profile between the groups in relation to the number of complications (P>0.05). …”
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128
Tests of a diamond field-assisted positron moderator
Published 2002“…Although positron re-emission was observed from the diamond surface, the re-emitted fraction was observed to decrease when a bias of 300 V was applied across the film. …”
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133
EPIDEMIOLOGY OF CHLAMYDIA TRACHOMATIS IN LATIN AMERICA AND THE CARIBBEAN: SYSTEMATIC REVIEW, META-ANALYSES, AND META-REGRESSIONS
Published 2022“…We conducted random-effects meta-regressions to identify sources of heterogeneity and possible predictors of high prevalence. Results: The pooled-mean urogenital CT prevalence was 8.2% (95% CI: 7.5-9.1) for general populations, 14.0% (95%CI: 12.7-15.4) for female sex workers, 10.8% (95% CI: 8.4-13.4) for men who have sex with men, male sex workers, and transgenders, 16.1% (95% CI: 12.6-19.8) for symptomatic women, 25.4 (95% CI: 18.6-38.5) for symptomatic men, 9.7% (95%CI: 6.1-14) for HIV-positive individuals and individuals in HIV-discordant couples, and 11.9% (95 CI: 8.5-15.8) for STI clinic attendees. …”
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134
The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis
Published 2023“…Results Random-effects meta-analysis of 3 studies including 244 patients demonstrated a significant decrease in plasma TMAO levels after statin treatment (WMD: -1.839, 95% CI: -2.391, -1.287, p<0.001; I2 :0). …”
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135
Inter-annual variability and distribution of aerosols during winters and aerosol optical thickness over Northeastern Pakistan
Published 2020“…Average over winters from 2007–2015, over the for four mega cities, Islamabad, Lahore, Faisalabad and Multan, the concentrations of sulfate were 5.06, 14.09, 14.29, 16.22 µg m−3, BC, were 1.5, 4.69, 4.46 4.52 µg m−3 and OC, were, 5.85, 17.32, 16.99 and 17.29 µg m−3, respectively. …”
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136
Advanced Hard Ctings: Towards A Whole New World
Published 2014“…The main problem with steel, is that it exhibits a relatively low hardness (below 10 GPa) which strongly decreases upon annealing above about 600 K. …”
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137
Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.
Published 2018“…In the case of D2HGDH protein, the mutations I147S and V444A that are positioned in the beta sheet region exhibited higher Root Mean Square Deviation (RMSD), decrease in compactness and number of intramolecular hydrogen bonds compared to the mutations N439D and D375Y that are positioned in the turn and loop region, respectively. …”
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138
Assessment of Dapagliflozin Effectiveness as Add-on Therapy for the Treatment of Type 2 Diabetes Mellitus in a Qatari Population
Published 2019“…Administration of dapagliflozin as an add-on therapy was found to decrease HbA1c significantly by 0.8 percentage point after 6 months (P = 0.006) and by 1.5 percentage point after 12 months (P = 0.062). …”
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139
Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
Published 2023“…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …”
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140
Mechanical and microstructure characterization of hard nanostructured N-bearing thin coating
Published 2015“…The main problem with steel, is that it exhibits a relatively low hardness (below 10GPa) which strongly decreases upon annealing above about 600K. …”
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