A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country حسب Zaghloul, Nancy

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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter... حسب Thirumal Kumar, D.

"…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…"
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Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis... حسب Anwar-Mohamed, Anwar

"…Upon knockdown of AhR and Nrf2 the MMA(V)-, DMA(V)-, and TMA(V)-mediated induction of both CYP1A1 and NQO1 proteins was significantly decreased. …"
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Pollution Characteristics of Particulate Matter (PM2.5 and PM10) and Constituent Carbonaceous Aerosols in a South Asian Future Megacity حسب Aslam, Afifa

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The impact of COVID-19 pandemic lockdown on smoking habits and lifestyle: A cross-sectional study حسب Khamees, Almu'atasim

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Effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic sars-cov-2 infected subjects: A pilot clinical trial in lebanon حسب Samaha, Ali A.

"…Objective: This study was designed to determine the efficacy of ivermectin, an FDA-approved drug, in producing clinical benefits and decreasing the viral load of SARS-CoV-2 among asymptomatic subjects that tested positive for this virus in Lebanon. …"
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Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy . حسب Djouhri, Laiche

"…Compared with control, we found in STZ-rats with established pain hypersensitivity (5 weeks post-STZ) several significant changes including: (a) A 23% increase in the incidence of spontaneous activity (SA) in Aβ-LTMs (but not C-mechanosensitive nociceptors) that may cause dysesthesias/paresthesia suffered by DPNP patients, (b) membrane hyperpolarization and a ∼85% reduction in SA rate in Aβ-LTMs by K7 channel activation with retigabine (6 mg/kg, i.v.) suggesting that K7/M channels may be involved in mechanisms of SA generation in Aβ-LTMs, (c) decreases in AP duration and in duration and amplitude of afterhyperpolarization (AHP) in C-and/or Aβ-nociceptors. …"
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Investigation Into the Effects of Non-Linear Loading of Domestic Power Network on Home Appliances حسب Hossain, Ajad

"…A power network is shown for a domestic house in Fig. 1. …"
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. حسب P, Sneha

"…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …"
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In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway حسب Kuttikrishnan, Shilpa

"…Notably, higher expression levels of these genes showed reduced overall and progression-free survival in the CTCL patient cohort. FOXM1 and BUB1B expression exhibited a dose-dependent reduction in NSP-B-treated CTCL cells.FOXM1 silencing decreased cell viability and increased apoptosis via BUB1B downregulation. …"
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The expression of bile acid Receptor TGR5 in Adipose Tissue in Diet-induced obesity mice حسب Ahmed, Sumaya

"…In conclusion, obesity is associated with decrease in expression of TGR5 in different fat depots and treatment with anti-obesity drug (Sulforaphane) causes stepwise upregulation of TGR5 gene expression in epididymal white adipose tissue parallel stepwise decrease in body weight. …"
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Towards energy efficient and quality of service aware cell zooming in 5G wireless networks حسب Lateef, Hafiz Yasar

"…The exponential growth of mobile data traffic would lead to dense deployment of small base stations and eventually higher energy consumption in Fifth Generation (5G) wireless networks. We formulate a dynamic cell zooming and base stations sleep optimization algorithm for dense heterogeneous networks as a Linear Programming (LP) problem in order to not only minimize the system power consumption but also to guarantee the quality of service to end user. …"
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Vitamin K1 as a potential molecule for reducing single-walled carbon nanotubes-stimulated �-synuclein structural changes and cytotoxicity حسب Naskhi A.

"…The cytotoxicity of �-syn/SWCNTs co-incubated with vitamin K1 against SH-SY5Y cells was also carried out by MTT, LDH, and caspase-3 assays. …"
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Sliding mode control based dtc of sensorless parallel-connected two five-phase pmsm drive system حسب Kamel T.

"…This paper presents a sensorless direct torque control (DTC) combined with sliding mode approach (SM) and space vector modulation (SVM) to achieve mainly a high performance and reduce torque and flux ripples of a parallel-connected two five-phase permanent magnet synchronous machine (PMSM) drive system. …"
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Mycoremediation of Tunisian tannery wastewater under non-sterile conditions using Trametes versicolor: live and dead biomasses حسب Boujelben, Raouia

"…The phytotoxicity test showed that the decrease in the toxicity levels was significantly higher for live biomass, reaching 44.1% at pH = 5.5 and did not exceed 33% for dead biomass. …"
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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS حسب ELJILANY, ISLAM AHMED SAYED AHMED

"…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …"
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Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs حسب Salloum-Asfar, Salam

"…Decreased levels of let-7a-5p showed an increase of SP8 as described previously. …"
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Study of Magnetic Properties and Lattice Dynamics of the Cdx Co1-x Ferrite System by MossbauerEffect حسب Eissa, N. A. [نبيل عيسى]

"…The Neel temperature was found to decrease with increasing cadmium concentration. The reduced hyperfine magnetic fields for the A- and the B- sites were found to follow the Brillouin function and One-Third-Power Law. …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan, Sirin

"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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