Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation حسب El Hasasna, Hussain

"…No proliferative recovery was detected after RCE removal. Annexin V staining and PARP cleavage analysis revealed a minimal induction of apoptosis in MDA-MB-231 cells. …"
احصل على النص الكامل
احصل على النص الكامل

A Reverse MultipleChoice Based mLearning System حسب Karkar, AbdelGhani

"…Koorsse et al. [5] proposed a mobile based system that uses two multiple-choice assessment methods. …"
احصل على النص الكامل
احصل على النص الكامل

The role of type II FB (I):Tl+ defect in laser light generation and color image formation at the low coordination surface sites of AgBr: Ab initio calculations حسب Shalabi, A.S.

"…All relaxed excited states of the defect containing surfaces were deep below the lower edges of the conduction bands of the ground-state defect-free surfaces indicating that type II FB(I):Tl+ is suitable laser defect. The probability of orientational destruction of the two centers, attributed to the assumed saddle point ion configurations along the 〈1 1 0〉 axis, was found to decrease as the coordination number of the surface ions decreases. …"
احصل على النص الكامل
احصل على النص الكامل

Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats. حسب Tan, Yong Chia

"…This study investigated the effect of apocynin, an NADPH oxidase inhibitor and catalase, an H2O2 scavenger on Cyclosporine A (CsA) nephrotoxicity in Wistar-Kyoto rats. Rats received CsA (25mg/kg/day via gavage) and were assigned to vehicle, apocynin (2.5mmol/L p.o.), catalase (10,000U/kg/day i.p.) or apocynin plus catalase for 14 days. …"
احصل على النص الكامل
احصل على النص الكامل

Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens حسب Bhatti, Sheraz Ahmed

"…The birds were offered diets supplemented with OTA (0.15 and 0.3 mg/kg feed) and/or TM (0.5, 1.0 g/kg) for 42 days of age, and blood and tissue samples were collected to examine the oxidative stress, biochemical and histopathological parameters. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes حسب Posa, Aniko

"…Male Wistar rats were treated with 5% ethanol, 0.01 mg/kg OPA, 0.1 mg/kg OPA and 1.0 mg/kg OPA per os. …"
احصل على النص الكامل
احصل على النص الكامل

Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain حسب Mohammad H., Merii

"…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Involvement of caveolae in hyperglycemia-induced changes in adiponectin and leptin expressions in vascular smooth muscle cells حسب Ola, El Atab

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …"
احصل على النص الكامل
احصل على النص الكامل

Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat حسب Hamdy, D. A.

"…Normolipidemic and hyperlipidemic rats were administered a single intravenous dose of MDZ (5 mg/kg) with or without a single oral dose of racemic KTZ (40 mg/kg). …"
احصل على النص الكامل
احصل على النص الكامل

The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy حسب Abdelaziz, Iman Ahmed

"…This was significantly abolished in the presence of siRNA-OPN (20.2 fold decrease±0.12 of control) and (68.5±0.24% vs. 586.5±103.54% NHE1-infected). …"
احصل على النص الكامل

Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo) حسب Saragusty, Joseph

"…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …"
احصل على النص الكامل
احصل على النص الكامل

Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: Development, characterization and stability evaluation حسب Khan I.

"…Sorbitol-based proliposome tablets in a 1:15 w/w ratio were found to be the best formulation as it exhibited excellent powder flowability with an angle of repose of 25.62 � 1.08� and when compacted the resultant tablets had low friability (0.20 � 0.03%), appropriate hardness (crushing strength) (120.67 � 12.04 N), short disintegration time (5.85 � 0.66 min), and appropriate weight uniformity. …"
احصل على النص الكامل
احصل على النص الكامل

Heat-stress-induced changes in enzymatic antioxidant activities and biochemical processes in bell pepper (Capsicum annuum L.) seedlings حسب Bello, Adewale Suraj

"…At 40 and 32 °C, HS led to a decrease in chlorophyll a (4.327 mg g–1 FW), b (1.710 mg g–1 FW), total chlorophyll (5.202 mg g–1 FW), and total carotene (1.092 mg g–1 FW) compared to the control at 25 °C (chlorophyll a 5.383 mg g–1 FW, chlorophyll b 2.358 mg g–1 FW, total chlorophyll 6.692 mg g–1 FW, and total carotene 1.817 mg g–1 FW). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Tests of a diamond field-assisted positron moderator حسب Al-Qaradawi, I. Y.

"…Although positron re-emission was observed from the diamond surface, the re-emitted fraction was observed to decrease when a bias of 300 V was applied across the film. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells. حسب Al-Jaber, Hend

"…Hypoxia increased HIF1a gene expression by approximately 30% (P<0.01). …"
احصل على النص الكامل
احصل على النص الكامل

Synthesis of Metallocene Catalyzed Ethylene 1,7-Octadiene Copolymer: Effect of Copolymerization on Polymer Properties حسب Rahaman M.

"…In this article, metallocene catalyzed polyethylene homopolymer and ethylene 1,7-octadiene copolymers were synthesized and the produced polymers were characterized. …"
احصل على النص الكامل
احصل على النص الكامل

Inhibitory effect of sodium nitrite on corrosion of lead in 0.1 M sodium hydroxide solution حسب Mourad, M.Y.

"…The concentrations of NaNO2 employed are in the range 1-5×10-5. There is a linear relationship between the corrosion potential and the molar concentration of NaNO2. …"
احصل على النص الكامل

Reducing energy consumption of CO2 desorption in CO2-loaded aqueous amine solution using Al2O3/HZSM-5 bifunctional catalysts حسب Zhang X.

"…The aim of this work is to find a potential way for great decrease in CO2 capture energy requirement. …"
احصل على النص الكامل
احصل على النص الكامل

Work-from-home, electricity, and water: Evidence from COVID-19 in Qatar حسب Bernstein, David H.

احصل على النص الكامل
احصل على النص الكامل