Showing 241 - 260 results of 28,880 for search '(( 5 mean decrease ) OR ((( 50 ((we decrease) OR (a decrease)) ) OR ( 2 fold decrease ))))', query time: 0.87s Refine Results
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    Cytoskeletal Drugs Modulate Off-Target Protein Folding Landscapes Inside Cells by Caitlin M. Davis (5642156)

    Published 2020
    “…The decreased compactness and folding stability of PGK could be explained by the decreased extent of crowding induced by these drugs. …”
  4. 244

    GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

    Published 2021
    “…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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    Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

    Published 2023
    “…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC<sub>50</sub> value compared to cisplatin and low toxicity to normal cells. …”
  8. 248

    Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

    Published 2023
    “…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC<sub>50</sub> value compared to cisplatin and low toxicity to normal cells. …”
  9. 249

    Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

    Published 2023
    “…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC<sub>50</sub> value compared to cisplatin and low toxicity to normal cells. …”
  10. 250

    Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

    Published 2023
    “…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC<sub>50</sub> value compared to cisplatin and low toxicity to normal cells. …”
  11. 251

    Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

    Published 2023
    “…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC<sub>50</sub> value compared to cisplatin and low toxicity to normal cells. …”
  12. 252

    The <i>rcan-1</i> rearrangement allele decreases expression of <i>rcan-1</i>. by Yuehui Zhao (3146229)

    Published 2020
    “…The gene with the largest and most significant expression decrease was <i>rcan-1</i>. Red: p<0.01, log<sub>2</sub>(Fold Change) > 1. …”
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    RT-qPCR analysis of congenital diaphragmatic hernia lungs showed an increase in distal epithelial progenitor and a decrease in type 1 alveolar cells. by Tram Mai Nguyen (6597863)

    Published 2019
    “…<p>E17.5 CDH lungs demonstrated a decrease in mRNAs identifying alveolar epithelial type I cells (<i>Hopx</i>, <i>Pdpn</i>) while distal epithelial progenitor marker <i>Id2</i> was increased. …”
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    Mean decrease in accuracy (MDA) of top 15 urine metabolites. by Liam E. Broughton-Neiswanger (8447220)

    Published 2020
    “…Urine metabolites with a mean decrease in accuracy ≥ 0.004 in at least one post-treatment time point (2–5) were considered for inclusion in the predictive model.…”