Glycosylated Platinum(IV) Complexes as Substrates for Glucose Transporters (GLUTs) and Organic Cation Transporters (OCTs) Exhibited Cancer Targeting and Human Serum Albumin Binding... by Jing Ma (24574)

“…Glycosylated platinum­(IV) complexes <b>5</b>, <b>6</b>, <b>7</b>, and <b>8</b> (IC₅₀ 0.24–3.97 μM) had better antitumor activity of nearly 166-fold higher than the positive controls cisplatin (<b>1a</b>), oxaliplatin (<b>3a</b>), and satraplatin (<b>5a</b>). …”

Glycosylated Platinum(IV) Complexes as Substrates for Glucose Transporters (GLUTs) and Organic Cation Transporters (OCTs) Exhibited Cancer Targeting and Human Serum Albumin Binding... by Jing Ma (24574)

“…Glycosylated platinum­(IV) complexes <b>5</b>, <b>6</b>, <b>7</b>, and <b>8</b> (IC₅₀ 0.24–3.97 μM) had better antitumor activity of nearly 166-fold higher than the positive controls cisplatin (<b>1a</b>), oxaliplatin (<b>3a</b>), and satraplatin (<b>5a</b>). …”

Glycosylated Platinum(IV) Complexes as Substrates for Glucose Transporters (GLUTs) and Organic Cation Transporters (OCTs) Exhibited Cancer Targeting and Human Serum Albumin Binding... by Jing Ma (24574)

“…Glycosylated platinum­(IV) complexes <b>5</b>, <b>6</b>, <b>7</b>, and <b>8</b> (IC₅₀ 0.24–3.97 μM) had better antitumor activity of nearly 166-fold higher than the positive controls cisplatin (<b>1a</b>), oxaliplatin (<b>3a</b>), and satraplatin (<b>5a</b>). …”

Metabolite interaction network of the combined differentially abundant metabolites influenced by disease severity. by Catherine H Kagemann (22439364)

“…<p>The interactions between differentially abundant metabolites influenced by disease severity in individuals with A) mild TB and B) severe TB compared to the controls (p < 0.05, Benjamini-Hochberg FDR correction, absolute log2 fold change > 0.5). …”

Worm infestations and development of autoimmunity in children – The ABIS study by Johnny Ludvigsson (167260)

“…At 8 years in total 20.0% of the general child population had experienced a worm infestation; children who developed Type 1 diabetes, 21,3%, celiac disease 19,5% and JRA 18,8%. …”

Wind-Driven Ignition Behavior of Wildland Fuels: Experimental Insights Under Controlled Conditions by Shusmita Saha (19162790)

“…For example, in wheatgrass fuels, flaming ignition temperature rose from ~ 472°C to ~ 610°C as wind speed increased from 0.5 to 2.0 m/s, with a concurrent decrease in smoldering-to-flaming transition time from 105 to 61 seconds. …”

Intracellular pH Measurements Using Perfluorocarbon Nanoemulsions by Michael J. Patrick (1872154)

“…In rat 9L glioma cells loaded with nanoemulsion, the local pH of nanoemulsions was longitudinally quantified using optical microscopy and flow cytometry and displayed a steady decrease in pH to a level of 5.5 over 3 h, indicating rapid uptake of nanoemulsion to acidic compartments. …”

Impact of loss of <i>Hes1</i> on differentiation and proliferation in the second heart field. by Francesca Rochais (371680)

“…<p>(A) Immunochemistry with anti-MHC (left), anti-α-actinin (right) and anti-β-galactosidase antibodies in transverse sections through the caudal pharyngeal region of an E9.5 embryo carrying the <i>Mlc1v-nlacZ-24</i> transgene. …”

Evaluation of the articular cartilage in the knees of rats with induced arthritis treated with curcumin by Tiago Nicoliche (8566002)

“…Based on the results of this study, the curcumin treatment appeared to exert a protective effect on cartilage, as it did not result in an increase in cartilage thickness or in MMP-8 and MMP-13 expression but led to increased IHH, Col2, and SOX-5 expression and the number of chondrocytes.…”

Intracellular pH Measurements Using Perfluorocarbon Nanoemulsions by Michael J. Patrick (1872154)

“…In rat 9L glioma cells loaded with nanoemulsion, the local pH of nanoemulsions was longitudinally quantified using optical microscopy and flow cytometry and displayed a steady decrease in pH to a level of 5.5 over 3 h, indicating rapid uptake of nanoemulsion to acidic compartments. …”

HSPs Inhibits CKII Mediated TDP-43 Filament Assembly. by Yari Carlomagno (152800)

“…<p>Hsp90 can inhibit the polymerization of tau, and TDP-43 is a known substrate for Hsp90. To examine the effects of Hsp90 on CKII mediated rTDP-43 filament assembly, 2.5 µM TDP-43 was polymerized for 60 minutes with CKII in the presence of 0.0–2.5 µM Hsp90. …”

Evaluation of Tetrahydrobiopterin Therapy with Large Neutral Amino Acid Supplementation in Phenylketonuria: Effects on Potential Peripheral Biomarkers, Melatonin and Dopamine, for... by Shoji Yano (2937894)

“…<p><b>Overnight serum melatonin AUC (A) and Plasma phenylalanine concentrations (B) over the 4 phases.…”

MATTER ACCUMULATION AND PHOTOSYNTHETIC RESPONSES OF MACAW PALM TO CYCLICAL DROUGHT by CLENILSO SEHNEN MOTA (6150236)

“…After rehydration, the gs and E of plants with and without water stress was not different, however, A presented a significant difference. Leaf water potentials below -0.5 MPa reduced the intracellular and atmospheric CO2 ratio and increased water use efficiency, and values of -1.85 MPa, when both showed an increase and decrease, respectively. …”

Ligand activation of ELIC. by Iwan Zimmermann (117942)

“…Macroscopic currents from a membrane patch in the outside-out configuration were recorded at −60 mV in response to a fast exchange into solutions containing 5 mM cysteamine. …”

Double knockdown of <i>Gli1/Gli2</i> in XY gonads. by Kathryn S. McClelland (687254)

“…<p>(A–D) Knockdown of GLI1/GLI2 in the gonad: qRT-PCR showed that treatment with Gli1/Gli2MO (<i>n</i> = 6, 5, 5, 8) resulted in no significant downregulation in steroidogenic regulator <i>Sf1/Nr5a1</i> (A) but a significant downregulation in expression of steroidogenic pathway enzymes <i>Hsd3β</i> (B), <i>Cyp11a1</i> (C) and <i>Star</i> (D). …”

DataSheet1_Isothermal crystallization kinetics in bulk of olefin-based multiblock copolymers.pdf by Gaia Urciuoli (11725469)

“…The crystallization half time of the samples increases with increase of M_n and, for each sample, its logarithm increases linearly with a decrease of the undercooling by a factor of -0.155/°C, for the samples 1–4 and −0.031/°C, for the sample 5. …”

Respiratory Exchange Ratio (RER) in ADKD and ADOX WT and OB mice. by Kazuhisa Watanabe (426012)

“…<p>Mice were chow-fed, 10-week-old B6 (WT) or B6.V-Lep^ob/J (OB) males, at 4 to 5 days p.t. with adenovirus knockdown vectors expressing RNAi for <i>lacZ</i> or <i>Ildr2</i> or with adenovirus vectors over- expressing <i>GFP</i> or <i>Ildr2</i>. …”

General Health Questionnaire (GHQ12): new evidence of construct validity by Tulio Augusto Andrade Oliveira (14728698)

“…The study included 1,085 physicians with a mean age of 45.7 (SD = 10.6), mostly male (61.5%), married (72.6%) and Catholic (59.2%). …”

Reduced production of white blood cells (WBC) in <i>Iqgap2</i>^<i>-/-</i> mice. by Amr M. Ghaleb (668342)

“…Data are presented as the mean ± SEM. N = 3 per genotype/treatment (<b>A</b>), N = 5 per genotype/treatment (<b>B</b>), p-values indicating statistically significant differences are shown.…”

<i>bmm</i>-mediated regulation of triglyceride homeostasis affects life span and contributes to the sex difference in starvation resistance. by Lianna W. Wat (8339454)

“…The <i>p</i>-values are listed in the following order: difference between the <i>GAL4</i>/<i>UAS</i> genotype and the <i>GAL4</i> control/difference between the <i>GAL4</i>/<i>UAS</i> genotype and the <i>UAS</i> control. Asterisks indicate a significant difference between two sexes, two genotypes, or two time points (*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001). …”