GluN2A(D731N) enhances sensitivity to endogenous proton and zinc ions. by Kai Gao (120150)

“…Di-heteromeric (h2A-D731N), one-copy and two-copy mutant tri-heteromeric (D731N/2A and D731N/D731N) receptors show a decreased current ratio, indicating enhanced proton sensitivity. …”

Mortality of <i>C. maculatus</i> after 24h exposure to GO and GO-GA NPs. by Huda H. Elbehery (22492996)

Deletion of <i>bipA</i> in pathogenic <i>S</i>. Typhimurium strains resulted in reduced invasion into HCT116 cells. by Eunsil Choi (8271039)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

GluN2A(D731N) reduces the agonist potency. by Kai Gao (120150)

“…<p>(<b>A,B</b>) Representative TEVC recordings obtained from oocytes expressing WT GluN1/GluN2A (WT 2A) receptors (<b>A</b>) and GluN1/GluN2A(D731N) (2A-D731N) receptors (<b>B</b>) in which the currents were evoked by increasing concentrations (μM) of glutamate (in the presence of 100 μM glycine) at the holding potential of -40 mV. …”

Figure 6: Cytotoxicity of Peptoid TM5 in three-dimensional models of the human lung by Aaron Benjamin (17798162)

BMP7v reduced VEGFR2 and FGFR1 expression in endothelial cells. by Courtney M. Tate (555115)

“…Representative images (5X magnification) are shown. Upon BMP7v treatment, mean staining intensity for VEGFR2 and FGFR1 was statistically decreased (***, <i>p<</i>0.001) compared to PBS controls.…”

Increased anxiety- and depression-like behavior in W/W^v mice. by Sachiko Chikahisa (417256)

“…<p>(A) Anxiety-like behavior in an elevated plus maze in WT and W/W^v mice at baseline. …”

Determinants of TRIT1 critical for cy-tRNA^SerUCA-mediated TMS in <i>S</i>. <i>pombe</i>. by Abdul Khalique (5029442)

Cell-targeted transgenic control of 5HT_2AR levels in neurons and glia during the experience-dependent critical period. by Vanessa Kay Miller (19775496)

“…Two-way ANOVA with Tukey’s multiple comparison shows EB experience-dependent increase in 5HT_2A receptor levels in both transgenic controls (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 5.38 × 10⁻¹⁰, <i>elav</i>-Gal4; <i>p</i> = 0.0205), a significant decrease in 5HT_2A receptor levels in both RNAi conditions (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 4.63 × 10⁻¹⁰, <i>elav-</i>Gal4; <i>p</i> = 1.05 × 10⁻⁹), and a significant elevated EB response with glial <i>5HT</i>_<i>2A</i><i>R</i> OE (<i>n</i> = 10/condition, <i>p</i> = 2.36 × 10⁻⁹). …”

Alveolar macrophages lack CCR2 expression and do not migrate to CCL2-5 by Judy M Opalek (37109)

“…</p><p></p>ion) were pre-incubated with 1 μg/ml CCR5 blocking antibodies and subjected to a migration assay using CCL3 (1–100 ng/ml) as the chemoattractant. …”

Image 5_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tiff by Chao-Chao Chen (21090215)

Table 5_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx by Chao-Chao Chen (21090215)

DECREASE IN OFF-PEAK ELECTRICAL ENERGY DEMAND BY AGROINDUSTRIES DUE TO PHOTOVOLTAIC SOLAR GENERATION by Lucas de A. Viana (7234946)

Baseline Transmission (None) and Five Intervention Scenarios: Q, QI, QA, QIA, and QIAC by Joseph T Wu (31525)

“…Therefore, the rate of transmission decreased by 75% within a peer group when one of two infected individuals complied with quarantine and by 96% if both did. …”

Body weight, body composition and glucose metabolism data. by Ditte Olsen Lützhøft (10837857)

Clusterin (<i>Clu</i>) expression is altered by aging in human and mouse organs and <i>Clu</i> expression is decreased in long-lived <i>Pit1</i>(<i>dw</i>/<i>dw</i>) mice (liver an... by William R. Swindell (175427)

Scaling exponent α for the whole measuring period 1980–2000 as a function of publication year; numbers are the averages of successive five-years blocks, each five-years block is lo... by Anthony F. J. van Raan (7517696)

Kaplan-Meier plots of breast cancer patient survival based on WDR5 expression. by Xiaofeng Dai (793874)